What is the mechanism of Paracetamol (Acetaminophen)?
Inhibits CNS prostaglandin synthesis; weak peripheral anti-inflammatory effect
Used for mild-moderate pain and fever.
What are the uses of Paracetamol (Acetaminophen)?
Commonly used as a first-line treatment for musculoskeletal pain.
What is the maximum dose of Paracetamol (Acetaminophen) per day?
4g/day
Overdose can lead to hepatotoxicity.
What are the osteopathic considerations for Paracetamol (Acetaminophen)?
Important for osteopathic treatment planning.
What is the mechanism of Codeine?
Opioid receptor agonist; converted to morphine in liver
Used for moderate pain.
What are the side effects of Codeine?
Requires caution during treatment.
What is the dose of Codeine?
15-60mg every 4-6 hours
Important for effective pain management.
What is the mechanism of Ibuprofen?
COX-1/COX-2 inhibition → reduces prostaglandins
Used for pain, inflammation, and fever.
What are the side effects of Ibuprofen?
Important to consider during treatment.
What is the maximum dose of Ibuprofen per day?
2.4g/day
Important for safety and efficacy.
What are the osteopathic considerations for Ibuprofen?
Critical for treatment planning.
What is the mechanism of Amitriptyline?
Inhibits serotonin/norepinephrine reuptake; blocks sodium channels
Used for neuropathic pain, migraine prophylaxis, chronic pain, and depression.
What are the side effects of Amitriptyline?
Important to monitor during treatment.
What are the uses of Sertraline?
Commonly prescribed SSRI.
What is the dose of Gabapentin?
300-3600mg daily (divided doses)
Important for managing neuropathic pain.
What are the side effects of Gabapentin?
Important to consider in treatment.
What is the mechanism of Propranolol?
Blocks β1 and β2 adrenergic receptors
Used for hypertension, angina, arrhythmias, migraine prophylaxis, and anxiety.
What are the side effects of Propranolol?
Important to monitor during treatment.
What are the osteopathic considerations for Warfarin?
High risk for bleeding.
What are the absolute contraindications to HVLA/deep techniques?
Critical for patient safety.
What are the relative contraindications for treatment?
Important to assess before treatment.
What is the key feature of Statin Myalgia?
Important for differential diagnosis.
What is the mechanism of Metformin?
Reduces hepatic glucose production; increases insulin sensitivity
Used for Type 2 diabetes.
What are the osteopathic considerations for PPIs (Omeprazole)?
Important for treatment planning.