Etidronate
Used for Paget Disease
Etidronate, it works like all other bisphosphonates in that it reduces osteoclastic activity.
UNLIKE the other bisphosphonates, it PREVENTS bone calcification.
for this reason etidronate is indicated for short term use only - 2 weeks to 3 months. If long term use is employed you run the risk of osteomalacia
Alendronate
Osteoporosis, Not Paget Dx
Plicamycin
Paget Dx
RNA synthesis inhibitor
Adenosine
Identify +/- Terminate SVT
Amiodarone
SVT
VT
Slows impulse generation and/or conduction of SA/AV nodes
When is Amiodarone contraindicated?
Bradyarrhythmias
IV glucagon
Used to treat CCB and/or Beta-Blocker toxicity
S/Sx of Exertional Heat Stroke
- Acute Confusion Extreme Hyperthermia (> 40.5°C)
Malignant Hyperthermia is often induced by which medications?
Halothane
Succinylcholine
Fluphenazine
“Typical” Anti-psychotic
Commonly injected Q2-3weeks in patients with POOR compliance
More potent than haloperidol (Inc. side effect profile)
can cause hypothermia by inhibiting the bodies shivering response and/or autonomic thermoregulation
Avoid prolonged cold exposure
MC side effects of amytripiline
- WEIGHT GAIN
- dizziness
- insomnia
MC side effects of cephalexin
- rash
- vomiting
- diarrhea
- abdominal pain
Tolterodine
Urge Incontinence
Overactive Bladder Sx
Vaginal Estrogen
- Urinary incontinence with concomitant vaginal atrophy
Flecainide, Propafenone
Class IC anti-arrhythmics
Tx: AFib in patients with STRUCTURALLY NORMAL hearts
- slowest rate of drug binding & dissociation from SC
- QRS & QT prolongation are normal occurrences EXCEPT in faster HR given use dependence of the drug.
Digoxin
ATP-ase-dependent Na+/K+ pump
- enhances vagal tone
- slows conduction through AV node
- used in older, sick hearts to enhance automaticity and delay after-depolarizations.
Side effects:
- bradyarrhythmias (younger, healthier patients)
- Ventricular ectomy & tachyarrhythmias (older patients with underlying cardiac dx)
Use dependence QRS / QT prolongation occurs with which anti-arrhytmic Rx?
- Class IC»_space;> IB, IA
2. Class IV
MC side effects of TMP-SMX
- Rash
- Neutropenia
- Hyperkalemia
- Elevated Transaminases
Need to treat PCP PNA but patient is sulfa allergic - what do you use?
What do you need to take into consideration when looking at these other drug regimens?
(A) IV Pentamidine
(B) PO Atovaquone
(C) Trimethoprim + Dapsone
(D) IV/PO Clindamycin + PO Primaquine
Dapsone: Hemolytic Anemia in G6PD Df.
Primaquine: Methemoglobinemia, Hemolytic Anemia in G6PD Df.
