Methenamine

Question 1

Good or bad absorption from GI tract?

Answer 1

Good

Question 2

Good or bad bioavailability?

Answer 2

Good

Question 3

___________ of dose can be hydrolyzed to formaldehyde by __________

Answer 3

10-30%

gastric acid

Question 4

Excretion?

Half life?

Answer 4

Renal

3-4 hours

Question 5

___________ form contains dye tartrazine which may cause allergic rx in ________ patients

Answer 5

Hippurate

Asthma

Question 6

Avoid in ________ because of ammonia byproduct

Avoid in _________ because acid forms could cause systemic acidosis

Answer 6

hepatic insufficiency

renal failure

Question 7

All ___________ susceptible to formaldehyde

Answer 7

bacteria and fungi

Question 8

At adequate urine ph (5.5) hydrolyzed to __________ which kills by

Answer 8

formaldehyde

denaturing proteins