A patient being treated for Plasmodium vivax malaria develops jaundice and dark urine after starting primaquine. Peripheral smear shows bite cells. What is the most likely underlying condition?
Glucose-6-phosphate dehydrogenase (G6PD) deficiency
What virulence factor of E.coli is the cause of sepsis directly
Lipid A is the major virulence factor of lipopolysaccharides that induces macrophages to release cytokines (eg, IL-1, tumor necrosis factor-alpha), leading to the manifestations of septic shock (eg, end-organ dysfunction).
What is the major virulence factor of meningtitis in E. coli
K1 capsular antigen
what happens when an anesthetic has a high lipid solubility
It has a faster onset of sedation and rapid recovery!