Microbiology

Question 1

Treatment of syphilis and verification?

Answer 1

IM penicillin G

Non-treponemal (RPR, VDRL) titer followed by 4x drop 6-12 month later

Question 2

Mechanism of action of echninocandins?

Answer 2

“Penicillin of fungus”
Inhibits 1,3-beta-glucan synthase for the cell wall
Caspofungin (Cancidas)

Question 3

Diarrhea of HIV

Answer 3

1) Cryptosporidium (CD4 <200)
- severe watery diarrhea w/ low grade fever
2) Microsporidium (CD4 <100)
- watery diarrhea w/ crampy abd pain and NO fever
3) MAC (CD4 <50)
- watery diarrhea w/ HIGH fever
4) CMV (CD4 <50)
- frequent small volume diarrhea w/ blood

Question 4

Blastomycosis

Answer 4

Systemic affects skin and bones
Broad based budding yeast
Itraconazole or amphotericin B

Question 5

Ramsay hunt syndrome

Answer 5

Vzv causing Bell’s palsy