Midterm 1 Flashcards by Emma Young

Q

What conditions favor SN2?

A

Methyl > 1* > 2* > 3*
Charged nucleophile
Polar aprotic solvent
Not bulky

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Q

How do you decide between SN1 and SN2?

A

structure of the nucleophile (charge)
structure of the electrophile (alkyl halide)
solvent (protic/aprotic)
LG ability

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