Subcutaneous
Innermost layer of skin (fat), lying over muscle and bone
Dermis
-Layer above subcutaneous
-contains no skin cells
-contains protective mast cells and macrophages
Epidermis
-Outermost layer of skin
-first line of defense
ABCDE of skin cancer
-Asymmetry of shape
-Border irregularity
-Color variation
-Diameter greater than 1/4 inch
-Evolving size/shape/color
Potential condition of white or paleness skin
-edema
-blood loss
-albinism
-vitiligo
Potential condition of yellow/orange skin
-liver disorders
-chronic kidney disease
Potential condition of red or hyperpigmentation in dark skin
-inflammation
-fever
-alcohol intake
Underlying cause of white or pale skin
-decreased blood flow to skin
-decreased hemoglobin level
Underlying cause of yellow/orange skin
-Increased total serum bilirubin level (jaundice)
-increased serum carotene level
Underlying cause of red or hyperpigmentation of dark skin
Increased blood flow (vasodilation)
Underlying cause of blue skin
-increase in deoxygenated blood (cyanosis)
-bleeding from vessels into tissue
Underlying cause of reddish blue skin
-increased overall amount of hemoglobin
-decreased peripheral circulation
Potential conditions of white nail color
-shock
-anemia
-myocardial infarction
Potential conditions of yellow/brown nail colors
-jaundice
-psoriasis
-diabetes
-cardiac failure
Potential conditions of red nail color
-bacterial endocarditis
-trauma
Potential conditions of blue nail color
-respiratory failure
-methemoglobinuria
Normal nail shape
Angle of 160 degrees
Early clubbing nail shape & significance
180 degrees (hypoxia, lung cancer)
Late clubbing and significance
Exceeds 180 degrees (hypoxia, emphysema, COPD)
Early koilonychias
Flattening of nail (iron deficiency,poorly controlled diabetes)
Late koilonychias
Concave curvature (psoriasis, irritants)
Beaus lines (grooves)
Horizontal depressions in nail plates
Pitting in nails
Small, multiple pits (psoriasis)
Acute paronychia
Inflammation of skin around nails