Diabetes Mellitus
Chronic multisystem disease caused by abnormal insulin production, impaired insulin utilization, or both.
Insulin
Hormone produced by β cells that lowers blood glucose and promotes glucose transport.
β cells
Cells in the islets of Langerhans that produce insulin.
Islets of Langerhans
Pancreatic cells responsible for hormone production including insulin.
Hyperglycemia
Elevated blood glucose level.
Hypoglycemia
Low blood glucose level.
Type 1 DM
Autoimmune destruction of pancreatic β cells leading to little or no insulin production.
Autoimmune destruction
Immune system attacks and destroys β cells.
Immune mediated disease
Disease caused by immune response against body tissues.
Type 2 DM
Insulin resistance with decreased insulin secretion over time.
Insulin resistance
Body cells do not respond properly to insulin.
Obesity
Major risk factor causing adipose tissue resistance to insulin.
Heredity
Genetic predisposition to diabetes.
Multigravida with large babies
Risk factor for developing Type 2 DM.
Polyuria
Sign or symptom associated with abnormal blood glucose levels.
Polydipsia
Sign or symptom associated with abnormal blood glucose levels.
Polyphagia
Sign or symptom associated with abnormal blood glucose levels.
Warm flushed dry skin
Sign or symptom associated with abnormal blood glucose levels.
Tachycardia
Sign or symptom associated with abnormal blood glucose levels.
Nausea/Vomiting
Sign or symptom associated with abnormal blood glucose levels.
Abdominal pain
Sign or symptom associated with abnormal blood glucose levels.
Kussmaul’s breathing
Sign or symptom associated with abnormal blood glucose levels.
Fruity odor of breath
Sign or symptom associated with abnormal blood glucose levels.
Altered LOC
Sign or symptom associated with abnormal blood glucose levels.