What helps initial mineralisation of dentine?
Matrix vesicles
After matrix vesicles, what is the subsequent mineralisation by?
heterogeneous nucleation
What are the matrix vesicles
They are vesicles produced by cells which contain high concentrations of Ca2+ and (PO4)3-
They are released into extracellular tissue
and the crystals grow and rupture the vesicle
What is the function of the matrix vesicles?
Provide an ideal microenvironment for crystal formation and growth
They help initiate mineralisation in mantle dentine and bone mineralisation