1
Q
What is needed to help paracetamol poisoning? What does it do?
A
- Start N-acetylcystine.
- Increases reactive intermediate to stable metabolite conversion.
- Increases glutathione transferase activity.
2
Q
What does N-acetylcystine correct in paracetamol overdose?
A
- Coagulation defects
- Fluid electrolyte and acid base balance
- Renal failure
- Hypoglycaemia
- Encephalopathy
3
Q
What are some paracetamol induced liver failure poor prognosis indicators?
A
- Late presentation
- Acidosis
- Prothrommbin time > 70 sec
- Serum creatinine ≥ 300 µmol/l
- Consider emergency liver transplant - otherwise 80% mortality
4
Q
WHAT IS KAPOSI’S SARCOMA CAUSED BY?
A
HHV-8 = human herpes virus 8
