GPhC Exam > Miscellaneous > Flashcards

Miscellaneous Flashcards

(18 cards)

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1
Q

Evidence triangle order

A
  1. systematic reviews
  2. meta-analysis
  3. randomised controlled trials
  4. cohort studies
  5. case control studies
  6. case series
  7. reports
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2
Q

Target of statins

A

reduce non-HDL cholesterol by 40% in 3 months

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3
Q

Diabetes macrovascular complications

A
  • CVD
  • peripheral arterial disease
  • peripheral vascular disease
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4
Q

Diabetes microvascular complications

A
  • kidney disease
  • retinopathy
  • peripheral neuropathy
  • autonomic neuropathy
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5
Q

Diabetes metabolic complications

A
  • DKA (T1DM, within hours)
  • dyslipidaemia
  • hyperosmolar hyperglycaemic state (T2DM, over weeks)
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6
Q

Linagliptin vs sitagliptin

A

linagliptin better in reduced renal function

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7
Q

Clopidogrel and omeprazole interaction

A
  • increased clot formation
  • omeprazole reduces anti platelet effect of clopidogrel
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8
Q

theophylline antidote

A

activated charcoal

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9
Q

heparins antidote

A

protamine sulfate

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10
Q

Which co-morbidity increases risk of rhabdomyolysis with statins

A

Hypothyroidism

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11
Q

Ivabradine side effects

A
  • anti - anginal drug
  • Visual effects (luminous phenomena)
  • Headache
  • Bradycardia
  • Heart block
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12
Q

LMWH has a lower risk of what compared to unfractionated heparin

A
  • osteoporosis
  • heparin-induced thrombocytopenia
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13
Q

Black person with HTN and diabetes - most appropriate HTN tx

A

ARB

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14
Q

CK monitoring with statins

A

only monitor at baseline and if complaint of muscle aches

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15
Q

Which ethnic group require a pre-treatment screening test for HLA-B*1502 allele with carbamazepine

A

Thai or Han-Chinese

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16
Q

Neuroleptic malignant syndrome

Study These Flashcards
A
  • antipsychotics
  • C.VET.PLZ
17
Q

Rapid symptomatic relief of hyperthyroidism

18
Q

constipation in children 1st line

Study These Flashcards
A

macrogol (osmotic) with diet/lifestyle

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