are fibrillations associated with UMN or LMN issues
LMN
are fine motor movements controlled by upper or lower motor neurons
upper
in the spinal cord, flexors are located __ and extensors are located __
dorsally, ventrally
what is the electrolyte balance of endolymph
high in potassium, low in sodium
cardiac rhabdomyomas are associated with what condition
tuberous sclerosis
what gives rise to cell bodies of afferent neurons
neural crest cells
The cerebellum is a derivative of…
the metencephalon
A failure in the differentiation of neural crest cells during embryonic development can result in what deficit
absence of PNS ganglia in the abdomen
what cell type gives rise to CNS cell populations
neuroepithelial
how does GABA work
it binds to its receptor, which is a Cl- ion channel. the binding leads to an inful of Cl- and hyperpolarization, inhibiting action
which condition features flattening of the caudate nucleus
huntington’s
what neurotransmitter can lead to toxic cellular events if left in the synaptic cleft and not cleared out
glutamate. too much of it being left means hyperexcitation of neurons, which ultimately damages them.
During active movement, what does the discharge frequency of individual corticospinal neurons in the primary motor cortex influence
contraction strength of individual muscles
what is the significance of activating gamma motor neurons
keeps spindles responsive to stretch during muscle shortening
what is the function of local circuit neurons that span the cord to connect medial grey matter
they aid in postural control
what are signs of cerebellum issues
movements that are not executed according to plan/jerking movements
what are targets for DBS in parkinsons
substantia nigra and globus pallidus
what dopaminergic pathway is associated with schizophrenia
mesolimbic (midbrain to limbic system)
what does the mesocortical pathway do
dopaminergic pathway connecting the midbrain to the prefrontal cortex
what is the nigrostriatal pathway
dopaminergic pathway between substantia nigra and striatum
what is anterior cord syndrome
damage to the anterior2/3rds of the spinal cord causes bilateral LMN deficit at the level of the lesion, spinothalamic deficity, and UMN deficit below the lesion. basically, everything but DCML gets fucked