What does the double membrane contain?
Intermembrane space and matrix
Is the outer membrane permeable?
Very permeable
Is the inner membrane permeable?
much less permeable
Where is ATP synthase and respiratory chain enzymes located?
The cristae
What is found in the intermembrane space?
Metabolic substrate and generated ATP
What is found in the matrix?
-Ribsosomes
- Site of the TCA cycle
-Site of FA breakdown
Mitochondria DNA.
What does the density of mitochondria depend on?
Depends on the cell type
What type of cells have high numbers of mitochondria?
-Muscle
-Neural Tissue
- Liver
- Kidney
- Brain
Function of mitochondria?
Production of ATP
Describe aerobic respiration?
involves complete oxidation of pyruvic acid presence of oxygen
Describe anaerobic respiration?
Absence of oxygen and results in the production of lactic acid
What does the mitochondria manufacture?
Fe-S clusters
What is Fe-S clusters needed for?
Co-Mediated electron transfer
Where is mitochondria inherited from?
It was inherited from the egg
Where is the mitochondria found on sperm?
On the Tail
Why is there never any male mitochondria passed on?
The tail which contain the mitochondria falls off
Describe the nature of Mitochondrial diseases
-Genetic
- Difficult to diagnose
- Produces lots of different symptoms
- Affects many different tissues and organs in the body
