Mitosis

Question 1

What type of experiments are used to analyse the genetics of the cell cycle?

Answer 1

Cell fusion experiments

Question 2

Example of a cell fusion experiment and how it works

Answer 2

When a cell in S phase is fused with a cell in G1 phase, S phase is activated in the original G1 nucleus.

This suggests that there is a dominant signal in the S phase.

Question 3

What is MPF maturation promoting factor ?

Answer 3

Cyclin a Cdk complex which promotes entrance into M phase from G2 phase in the cell cycle