MOA Flashcards by Dr. Karthikeyan Karthikeyan

Q

Cycloserine

A

Alanine racemase
L ALA -> D ALA

Alanine Ligase
D ALA + D ALA -> D ALA - D ALA

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Q

Fosfomycin

A

Enolpyruvate transferase
UDP - NAG –> UDP - NAM

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Q

Bacitracin

A

Bactoprenol
NAG NAM transmembrane transfer

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Q

Vancomycin

A

Transglycosylase
Chain elongation

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Q

β lactams

A

Transpeptidase
Cross linking

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Q

Topiramate

A

Na+ blocker
Carbonic anhydrase inhibitor
↑GABA
↓Glutamate

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Q

Cyclosporine A
Tacrolimus

A

Calcineurin inhibitor

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Q

Sirolimus

A

mTOR inhibitor

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Q

Basiliximab

A

IL 2 receptor
Anti CD25

Used to prevent graft rejection

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Q

Mycophenolate

A

IMP dehydrogenase inhibitor

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Q

Azathioprine

A

6 MP inhibitor

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Q

Sildenafil

A

PDE 5 blocker → ↑cGMP → vasodilation

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