Pharm test #3 > MOA by class > Flashcards

MOA by class Flashcards

(15 cards)

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1
Q

Penicillins MOA

A

Bind PBP- inhibit crosslinking

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2
Q

aminoglycosides MOA

A

Irreversibly bind 30S - inhibit protein synthesis

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3
Q

cephalosporins MOA

A

bind PBP - inhibit crosslinking

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4
Q

Monobactam MOA

A

Binds PBP-3 - inhibits crosslinking

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5
Q

glycopeptides MOA

A

bind D-ala D-ala

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6
Q

oxazolidinones MOA

A

bind 50S

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7
Q

carbapenems MOA

A

bind PBP-2

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8
Q

lipopeptides (daptomycin) MOA

A

membrane depolarization - inhibits DNA and protein synthesis

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9
Q

tetracyclines MOA

A

reversibily bind 30S

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10
Q

TMP-SMX MOA

A

inhibits PABA pathway - inhibits purine synthesis

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11
Q

fluoroquinolones MOA

A

inhibits topoisomerases II (DNA gyrase) and topoisomerase IV

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12
Q

metronizole MOA

A

inhibits DNA synthesis in Anaerobes

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13
Q

clindamycin MOA

A

Binds 50S

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14
Q

macrolides MOA

A

Bind 50S

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15
Q

streptogramins MOA

A

bind 50S

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Pharm test #3
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