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Question 1

33y/o pregnant female with hypertension.
which drug contraindicated?

Methyldopa
ramipril
labetalol
nifedipine
hydralazine

Question 2

22y/o male admitted to A&E with acute asthma attack.
which med cant be used?

ipratropium 
salbutamol
Mg sufate
hydrocortisone
montelukast

Question 3

briefly explain mechanism of action of
a) benzodiazepines

(2)

Question 4

briefly explain mechanism of action of
b) Ticagrelor

(2)

Question 5

briefly explain mechanism of action of
c) Fondaparinux

(2)

Question 6

4 SE of digoxin toxicity?

4

Question 7

describe how the INTRINSIC coagulation cascade -> clotting
explain how 2 named drug classes interfere with this cascade

(10 marks)

Answer 7

tissue damage (polyanions)stop XII -> XIIa (active form)this blocks XI -> XIablocks IX -> IXablocks VIIIa,PA,Ca2+

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