the coventional AH pathways is also called
corneoscleral
main structures in the conventional AH pathway
TM and SC
which AH pathway is IOP dependent
conventional path
the unconventional AH pathway is also called
uveoscleral
main structure in the unconventional path
ciliary muscle bundle
which AH pathway is IOP independent
unconventional path
what are 3 big factors that affect IOP
- peak in morning
- corneal thickness
- steroids
if a cornea is thicker than normal, how will the IOP be affected
abnormally high reading
2 ways to obstruct outflow
- occlusive angle
- injury to TM
what are possible causes of an occlusive angle (5)
- severe diabetes
- uveitis
- hyphema
- pseudoexfoliative glaucoma
- pigment dispersion glaucoma
what are possible causes of injury to TM (2)
- fuch’s heterochromic iritis
- glaucomatocyclitic crisis
an acute rise in EVP result in what
1:1 ratio of increase IOP
4 main aging changes to the anterior chamber
- reduced depth
- reduced uveoscleral outflow
- extracellular matrix plaque in TM
- increased outflow resistance in the TM and SC
what has a big effect on the anterior chamber depth
cortical cataract
whey is there a reduction in uveoscleral outflow with age
increase in the amount of connective tissue in ciliary muscle
5 components of vitreous
- water
- collagen
- hyaluronic acid
- vitreal cells
- vitamin C
what makes up 99% of the vitreous
water
what 2 components give vitreous the gel like texture
collagen interacting with hyaluronic acid
4 major functions of the vitreous
- support
- diffuse barrier
- metabolic buffer
- transparency
what can affect the “support” function of the vitreous
PVD
also macular edema
what can affect the “ metabolic buffere” function of the vitreous
- reduce neovascularization in retina
- neovascular galucoma
- NSC
what can affect the “ transparency” function of the vitreous
- synchisis scintillation
- asteroid hyalosis
accumulation of choesterol within vitreous
synchisis scintillations
accumulation of calcium within vitreous
asteroid hyalosis
