MODULE 1-RESPIRATION Flashcards

(48 cards)

1
Q

Per the transcript, state the numbers of NADH and FADH2 produced per glucose, and the approximate ATP yield from the electron transport chain.

A

6 NADH, 2 FADH2; ~34 ATP

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2
Q

What is the chemical formula for one molecule of glucose as stated?

A

C6H12O6

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3
Q

According to the transcript, glucose plus oxygen is converted into which products?

A

6 CO2, 6 H2O and ATP

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4
Q

Which three parts make up an ATP molecule?

A

Adenine, ribose, and three phosphates

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5
Q

Glycolysis yields ATP when converting one glucose to pyruvate. Which statement best gives the concise net ATP yield per glucose?

A

2 ATP per glucose

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6
Q

What is the net ATP and NADH produced by glycolysis per glucose?

A

2 ATP and 2 NADH

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7
Q

Explain the roles of NAD+ and FAD and why fermentation occurs without oxygen.

A

NAD+ and FAD accept electrons during metabolism, becoming NADH and FADH2 which shuttle electrons to the electron transport chain to drive ATP production; without oxygen the chain cannot accept electrons, so cells regenerate NAD+ by reducing pyruvate (fermentation) to keep glycolysis producing ATP.

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8
Q

What term does the transcript use for using water to break down ATP (water + lysis)?

A

Hydrolysis

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9
Q

Which statement best summarizes the overall aerobic respiration outcome for one glucose molecule?

A

Six CO2, six H2O, and ATP energy

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10
Q

DEFINE RESPIRATION

A

AN INTRACELLULAR OXIDATION PROCESS IN WHICH COMPLEX ORGANIC SUBSTANCES ARE BROKEN DOWN INTO SIMPLER SUBSTANCES WITH STEPWISE RELEASE OF ENERGY.

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11
Q

State the net number of ATP molecules produced by glycolysis per glucose.

A

2 ATP

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11
Q

Which statement best describes glycolysis?

A

C. Cytoplasmic conversion of glucose to two pyruvate, net 2 ATP

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12
Q

Which statement best explains why ATP releases energy when it becomes ADP?

A

Repulsion between terminal phosphates leads to hydrolysis and phosphate loss

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13
Q

Which statement best explains oxygen’s role in the electron transport chain?

A

Terminal electron acceptor

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14
Q

Which molecule enters the link reaction from glycolysis?
A. Glucose
B. Pyruvate
C. Acetyl-CoA
D. Citrate

A

B. Pyruvate

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15
Q

Define “oxidative phosphorylation.”

A

The synthesis of ATP using energy released from electron transport and proton gradient across the inner mitochondrial membrane.

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16
Q

How many NADH are produced per glucose molecule during glycolysis?

A

2 NADH

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17
Q

A student investigates respiration in germinating seeds using a respirometer. If the potassium hydroxide in the apparatus is removed, what result will they observe?

A

CO₂ produced will not be absorbed, so the fluid marker will not move, making it seem as if no oxygen was consumed.

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18
Q

Which enzyme catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate?
A. Hexokinase
B. Pyruvate kinase
C. Phosphofructokinase
D. Dehydrogenase

A

C. Phosphofructokinase

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19
Q

Explain why anaerobic respiration is less efficient than aerobic respiration.

A

In anaerobic respiration, glucose is only partially oxidized to lactate or ethanol, producing 2 ATP per glucose instead of ~32 ATP in aerobic respiration.

20
Q

The final electron acceptor in aerobic respiration is ________.

21
Q

A mitochondrion is treated with a chemical that makes the inner membrane permeable to protons. Predict the effect on ATP production.

A

Proton gradient collapses; chemiosmosis cannot occur, so ATP synthesis stops.

22
Q

Where does the Krebs cycle occur?
A. Cytoplasm
B. Mitochondrial matrix
C. Cristae
D. Intermembrane space

23
Q

Outline the main products of one turn of the Krebs cycle.

A

3 NADH, 1 FADH₂, 1 ATP (as GTP), 2 CO₂.

24
Why is oxygen described as the “final electron acceptor” in the ETC?
It accepts electrons from Complex IV and combines with protons to form water, allowing the chain to continue.
25
During strenuous exercise, muscle cells produce lactic acid. What is the consequence if this lactic acid is not removed?
pH of muscle tissue drops, enzyme activity decreases, leading to fatigue and cramp.
26
Compare the ATP yield of aerobic vs anaerobic respiration and explain the reasons for the difference.
Aerobic respiration yields ~32 ATP per glucose, while anaerobic yields only 2. This is because aerobic uses ETC and oxidative phosphorylation, completely oxidizing glucose to CO₂, whereas anaerobic only oxidizes glucose to lactate/ethanol.
27
Which coenzyme carries electrons from glycolysis to the ETC? A. NADH B. FADH₂ C. NADPH D. Coenzyme A
A. NADH
28
What structural feature of the inner mitochondrial membrane increases efficiency of respiration?
Its folds (cristae), which increase surface area for ETC proteins and ATP synthase.
29
If cyanide is introduced into a cell, oxygen is still present but ATP production drops drastically. Explain why.
Cyanide inhibits cytochrome oxidase (Complex IV), preventing electron transfer to oxygen. ETC halts, no proton gradient forms, so oxidative phosphorylation stops.
30
Define “substrate-level phosphorylation.”
ATP production by direct transfer of a phosphate group from a substrate molecule to ADP, without involvement of ETC.
31
How many ATP are produced directly in glycolysis (gross yield)? A. 2 B. 4 C. 6 D. 8
B. 4
32
What is the immediate product when acetyl-CoA enters the Krebs cycle?
Citric acid (citrate)
33
A scientist isolates mitochondria and supplies them with NADH but no ADP. What happens to oxygen consumption?
Oxygen consumption slows/stops because without ADP, ATP synthase does not function, proton gradient builds up, halting ETC.
34
Why is the Krebs cycle described as amphibolic?
It participates in both catabolism (oxidizing acetyl-CoA for energy) and anabolism (providing intermediates for biosynthesis).
35
How many net ATP are produced per glucose in glycolysis? A. 0 B. 2 C. 4 D. 8
B. 2
36
Yeast fermenting glucose produces bubbles in bread dough. What causes the bubbles?
CO2 released during alcoholic fermentation.
37
List three adaptations of mitochondria that allow efficient ATP production.
(1) Cristae provide large surface area. (2) Matrix contains Krebs enzymes. (3) Has its own DNA/ribosomes for protein synthesis.
38
In the absence of oxygen, human muscle cells convert pyruvate into ________.
Lactate
39
Describe the process of chemiosmosis and explain its role in ATP production.
Electrons pass through ETC, pumping protons into intermembrane space. Proton gradient drives protons through ATP synthase back into matrix, causing conformational change that phosphorylates ADP to ATP.
40
How many CO₂ molecules are released per glucose during link reaction?
2 (1 per pyruvate)
41
Seeds are placed in a respirometer at low temperature. What is the expected effect on the rate of respiration?
Respiration slows because enzymes are less active at lower temperatures.
42
Which stage of respiration does NOT occur in mitochondria? A. Krebs cycle B. Link reaction C. Glycolysis D. Oxidative phosphorylation
C. Glycolysis
43
Which of the following can be used as a respiratory substrate in emergencies when glucose is low? A. Glycogen only B. Proteins only C. Fats and proteins D. Lactate only
C. Fats and proteins
44
Which tissue in humans relies almost exclusively on aerobic respiration due to high energy demand? A. Red blood cells B. Skeletal muscle (fast twitch) C. Cardiac muscle D. Liver
C. Cardiac muscle
45
Why do red blood cells respire only anaerobically?
They lack mitochondria, so respiration is limited to glycolysis.
46
A marathon runner continues breathing heavily even after finishing a race. Explain why.
They are repaying oxygen debt to metabolize lactate, restore ATP and creatine phosphate, and reoxygenate hemoglobin/myoglobin.
47
Which coenzyme is permanently attached to Complex II of the ETC? A. NAD+ B. Coenzyme A C. FAD D. Cytochrome C
FAD