module 2 Flashcards

molecules of life (39 cards)

1
Q

how can only around a dozen chemical elements generate the diversity of molecules that make up living organisms

A

basic features of chemistry:

  • each element contains only 1 types of atom -> basic unit of matter
  • C, H, O, N, P
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2
Q

what are the components of an atom

A

nucleus, protons and neutrons

electrons move around nucleus

electrons move around nucleus in a region of space -> orbitals (can hold max 2 electrons)

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2
Q

how are molecules formed

A

atoms combining with other atoms

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3
Q

what is atomic number and atomic mass

A

of protons

of protons + # of neutrons

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4
Q

what are valence electrons

A

electrons found in outermost orbitals of an atom

determines # of bonds an atom can make

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5
Q

what are covalent bonds

A

valence electrons shared in a molecular orbital

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6
Q

what is a polar covalent bond

A

when there is an unequal sharing of electrons

ex. water -> O2 is more electronegative and attracts electrons more than H

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7
Q

what is a cation

A

atom with positive charge (extra protons relative to electrons)

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7
Q

what is a nonpolar covalent bond

A

equal sharing of electrons

atoms have the same or nearly the same electronegativity

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8
Q

what is an ionic bond

A

atom “steals” an electron from another when there is a significant difference in their electronegativity

ex. NaCl -> Cl steals an electron from Na, sodium is positive and Cl is negative

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9
Q

what are the starting substances and ending substances of chemical reactions

A

reactants and products

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9
Q

what is an anion

A

atom with negative charge (extra electrons relative to protons)

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10
Q

what is essential to water’s biological function

A

its polarity

depending on how molecules reacts with water they can be described as:

hydrophilic (form H bonds with water)

or

hydrophobic (do not form H bonds with water)

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10
Q

what happens when salts are placed in water

A

Na+ and Cl- are pulled apart and become surrounded by water molecules -> salt dissolves in water

bc of partial positive charge on H associates with negative charge on Cl and partial negative charge on O associates with + charge on Na

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11
Q

what are chemical reactions

A

breaking and forming of chemical bonds

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12
Q

what is the universal solvent?

A

water -> can dissolve more types of molecules than any other molecule

12
Q

why is water the medium of life

A

most abundant molecule in biological organisms

13
Q

what is a hydrogen bond

A

weak bonds formed between an electronegative atom and a hydrogen atom that is already covalently linked to another atom

H atoms form H bonds with O and N

pair of shared electrons is closer to the electronegative atom

14
Q

why is pH important

A

for cellular function (ex protein structure or enzyme activity)

14
Q

what is pH

A

in a solution of water, some of the water molecules exist as protons (H+) and hydroxide ions (OH-)

measurement of concentration of protons (H+) in a solution

ranges from 0-14

pure water -> pH 7

solutions with pH less than 7 -> acidic

solutions with pH higher than 7 -> basic

15
Q

what are functional groups

A

change chemical character to carbon chains

chemical properties of their own

a N, O, P, or S in a functional grp is more electronegative -> form polar functional grps

methyl grp -> nonpolar functional grp

typically involved in reactions to combine simpler molecules to form polymers

15
Q

what are organic molecules

A

molecules that contain carbon

16
Q

what is the chemical significance of carbon

A

can combine with many other elements to forma wide variety of molecules

can form 4 covalent bonds -> combos of single/double bonds

can be linked to form chains/rings

ex. in methane, each of the 4 valence electrons share a molecular orbital with electron of one of the H atoms

16
Q

what are the 4 types of biological molecules

A
  1. proteins: structural support and assist chem rxns by acting as catalysts
  2. nucleic acids: encode and transmit genetic info
  3. carbohydrates: structural support for many organisms and source of energy
  4. lipids: make up cell membranes, store energy, important in cell communication
16
what is a condensation reaction
"making the chain" when monomers combine with each other to form covalent bonds -> release water molecules as a byproduct of synthesis requires energy
17
what are polymers
large molecules made up of building blocks called monomers biological chemicals
18
how are condensation and hydrolysis reactions sped up
by specific enzymes
18
what is a hydrolysis reaction
"breaking the chain" when polymers breakdown into monomers -> a water molecule si inserted across bond (splits water molecule) releases energy
18
what is the general structure of an amino acid
central alpha carbon is covalently linked to 4 grps: carboxyl (-COOH) amino (-NH2) hydrogen (H) R grp (side chain) - distinguishes one amino acid from another
19
what are functions of proteins
large variety of functions that is greater than any grp of macromolecules 1. enzymes -> catalysts that accelerate rate of chem rxns 2. transport -> across cell membranes, circulation 3. cell signalling/regulation -> ex. hormones, membrane proteins, intracellular messengers 4. movement -> of the cell itself via contractile proteins, flagella or within cell thru motor proteins 5. support -> cytoskeleton or proteins within extracellular matrix outside of cell 6. defense -> antibodies, complement proteins
19
what are polypeptides
amino acids that are covalently linked into linear polymers
20
what happens to amino acids at physiological pH 7.4?
carboxyl grp and amino gps are ionized amino acids have both positive and negative charges -> zwitterion
20
21
what are nucleic acids
information molecules, encode genetic info in sequence of nucleotides
21
what happens when peptide bonds form
carboxyl grp releases an oxygen atom and N loses 2 H atoms to produce water molecule 20 genetically encoded amino acid monomers -> order provides info carried out by protein sometimes 2+ polypeptide chains must combine to form mature protein
22
what are the 2 types of nucleic acids
1. deoxyribonucleic acid (DNA) - genetic material in all cellular organisms - contains info used to direct protein synthesis 2. ribonucleic acid (RNA) - key player in protein synthesis and regulation of gene expression
23
what bond joins amino acids
covalent bond
24
what are nucleotides composed of
1. nitrogen containing pyrimidine or purine 2. 5-carbon (pentose) sugar dna -> deoxyribose rna -> ribose 3. 1+ phosphate grps
24