Module 3 Flashcards

(52 cards)

1
Q

Q: What type of language is often preferred by the autism community?

A

A: Identity-first language (e.g., “autistic child”).

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2
Q

Q: Why do many autistic individuals prefer identity-first language?

A

A: Because autism is seen as part of their identity and not something shameful.

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3
Q

Q: Name a common myth about autism

A

A: That all autistic children have intellectual disability.
A: The belief that all autistic individuals have extraordinary abilities (savants)
A: The myth that autistic children do not care about other people.
A: The myth that autistic children do not want friends.
A: That vaccines cause autism.

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4
Q

Q: What are the two main defining characteristics of Autism Spectrum Disorder?

A

A: Impairments in social communication and restricted/repetitive behaviors.

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5
Q

Q: What does the word “autism” mean?

A

A: “Within oneself,” reflecting difficulty interacting with the external world.

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6
Q

Q: Why is autism called a “spectrum”?

A

A: Because symptoms vary widely in type and severity across individuals e.g. intelligence, language problems. Within child level of severity may change asexperience gains in social and cognitive skills

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7
Q

Q: What are the three DSM-5 social communication impairments in ASD? (need all 3 for diagnosis)

A

A: Social-emotional reciprocity, nonverbal communication deficits, and difficulty developing/maintaining/understanding relationships.

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8
Q

Q: What are the 4 DSM-5 restricted repetitive and stereotyped patterns of behaviour, interests and activities criteria in ASD? (need at least 2 for diagnosis)

A
  1. stereotyped or repetitive motor movements, use of objects or speech
  2. Insistence on sameness, inflexible adherence to routines, or ritualised patterns of verbal or nonverbal behaviour
  3. Highly restricted and fixed interests
  4. Hyper or hyporeactivity to sensory input or unusual interest in sensory aspects of environment
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9
Q

What is social-emotional reciprocity?

A

A: The ability to engage in back-and-forth social interactions.

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10
Q

Give examples of impairements in social-emotional reciprocity

A
  1. failure to initiate or respond to social interactions
  2. Joint attention deficits -> do not use eye contact to initiate e.g.
  3. Abnormal social approach and failure to engage in normal back-and-forth conversation
  4. reduced sharing of interests or emotions
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11
Q

Examples of nonverbal communicative behaviours

A
  1. Abnormalities in eye contact and body langauge (e.g. peering out corner of eye, eye contact maybe seen as socially threatening/uncomfy)
  2. Lack of facial expressions
  3. Poorly integrating verbal and nonverbal communication (saying i want magazine and pointing to it)
  4. Deficits in understanding and use of certain types of gestures -> protoimperative vs protodeclerative gestures
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12
Q
A
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13
Q

Q: What is a proto-imperative gesture?

A

A: A gesture used to request something or express a need.

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14
Q

Q: What is a proto-declarative gesture?

A

A: A gesture used to share interest in something with others.

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15
Q

Q: Which gesture type is more common in autism: proto-imperative or proto-declarative?

A

A: Proto-imperative gestures.

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16
Q

Examples of deficits in developing, maintaining and understanding relationships

A
  1. Difficulty in sharing imaginative play
  2. Difficulty making friends
  3. Impairment in adjusting behaviour to suit various social contexts
  4. Atypical level of interest in peers
    (deficit in ability to understand and respond to social info, not deficit in ability to bond with others)
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17
Q

Examples of restricted and repetitive behaviours and interests

A
  1. Highly restricted, fixated interests
  2. Repetitive speech (e.g. echolalia (repeating a word or phrase that someone else has said), idiosyncratic phrases)
  3. Self-stimulatory behaviours (e.g. hand flapping, rocking etc.)
  4. Insistence on sameness of behaviours
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18
Q

What are 3 theories that try and explain why autistic children engage in self stimulatory behaviour?

A
  1. Due to craving for stimulation to excite their nervous system
  2. It is a way of blocking out and controlling unwanted stimulation from the environment that is too stimulating
  3. Self stimulatory behaviour is maintained by the sensory reinforcement that it provides.
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19
Q

What are 2 other symptoms of ASD which are not focused on behaviours?

A
  1. Deficits in processing social emotional information
  2. Sensory and perceptual impairments
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20
Q

Examples of Deficits in processing social emotional information

A
  1. Difficulty understanding unspoken rules and social situations
  2. Difficulty understanding nonverbal emotional information (e.g. facial expressions)
  3. Difficulty understanding Theory of Mind (ToM)
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21
Q

Examples of sensory and perceptual impairments

A
  1. Oversensitivites and undersensitivities to certain stimuli (e.g. enjoy deep strong hug but dislike light touch)
  2. Overselective and impaired shifting of attention to sensory input (e.g. paying attention to both movement and sound of a person clapping)
22
Q

What are the two parts of autism assessment?

A
  1. Autism Diagnostic Interview-Revised (ADI-R)
  2. Autism Diagnostic Observation Schedule (ADOS-2)
23
Q

What is the ADI-R?

A
  • Structure interview conducted with the parents
  • Assesses behaviour in areas of reciprocal social interaction, communication and language, and patterns of behaviour
24
Q

What is the ADOS-2

A
  • semi structured assessment of communication, social interaction and imaginative play
  • Provides a 30-45 min observation period during which examiner provides child with numerous opportunities to exhibit behaviours that are part of diagnostic criteria
  • Examiner uses presses -> planned social activities that tend to elicit demonstration of social reciprocity skills, communication skills, and imaginative play -> e.g. having them tell a story based on pictures that has physicality to see if use gestures
25
What are the associated features of ASD?
1. Language deficits 2. Intellectual deficits and strengthsee
26
Language deficits in ASD kids stats
* 30-40% do not develop sufficient language abilities * autistic children who develop language usually do so before age 5
27
Intellectual Deficits and Strengths in ASD kids stats
* ~70% of autistic children have co-occuring intellectual impairment * ~25% have splinter skills or islets of ability -> 5% savants
28
Cognitive deficits associated with ASD
1. Deficits in general executive functioning: impairments in effective problem solving, inhibiting inappropriate behaviours, sustaining task performance, flexibly shifting from one task to another 2. weak central coherence: focus on details at expense of the big picture
29
What is the prevelance of ASD?
~1-2%
30
Gender difference in autism prevalence rates
4x more common in boys than girls
31
Give potential reasons for gender difference in ASD prevalence
* girls with comparable levels of symptom severity as boys less likely to be diagnosed * bias in diagnosis or girls may be better able to cope with same level of ASD symptoms if no co occuring intellectual disability
32
Race/Ethnicity differences in ASD prevalence
under identification of ASD in black and latino children -> black children 3x more likely than white to receive another diagnosis like ADHD before ASD
33
Age of Onset of ASD
* Early -> often identified by parents in the months preceding child's second birthday * diagnosis usually made in preschool period or later * earliest point in dev for reliable detection period -> 12-18 months
34
How come some individuals with ASD get diagnosed much later in childhood and adolescence?
because they may have higher functioning in verbal and intellectual abilities -> due to greater difficulty in identifying it.
35
What was autism initially thought to be caused by?
cold and unloving parents
36
What are the three main groups of causes of ASD?
* Problems in early development * Genetic influences * Brain abnormalities
37
Explain the pathway of ASD causes
1. Genetic susceptibility + experience environmental risk fastors in early dev 2. These vulnerabilities then contribute to -> altered neural circuitry + altered patterns of interactions between child and environment 3. Outcome -> either ASD or broader autism phenotype (can include less severe features of autism)
38
What are the three categories in prenatal development in which factors may contribute to ASD
1. Conception 2. Teratogens 3. Maternal illness
39
What are the two factors found in conception to be related to autism?
1. Parental age -> maybe due to men with autism take longer to have children, or maybe accumulation of spontaneous mutations in sperm throughout the father's life. 2. In Vitro Fertilisation
40
What are teratogens?
Substances that contribute to malformations of an embryo
41
Give two examples of teratogens that have been linked to ASD
1. Thalidomide (initially med for anxiety, trouble sleeping and morning sickness) 2. Valproic acid (used to treat epilepsy and mood swings -> possibly accelerates brain growth in fetus)
42
Give an example of a mental illness that contributes to autism
rubella
43
What are possible perinatal factors which may contribute to autism (REMEMBER EVIDENCE HAS BEEN INCONSISTENT)
* birth weight * duration of gestation * event around time of birth
44
What are the two ways in which genetic influences of ASD have been investigated?
* comorbidity between ASD chromosomal and gene disorders * family and twin studies
45
Give an example of a comorbidity between ASD and chromosomal + gene disorders
Fragile X syndrome -> most common inherited cause of intellectual disability with a higher rate of comorbid ASD (close to half of children with Fragile X have ASD (2-3% of ASD kids))
46
What are the findings of the family and twin studies for the genetic influences of ASD
* 70-90% concordance in identical twins * Large population based study found 38% heritability -> recent meta analysis found 64-91% heritability * Other family members may have broader autism phenotype
47
What is the purpose of molecular genetic studies
Try to figure out which specific genes play a role in disorder
48
What are the 2 primary approaches of molecular genetics
1. Targeted molecular studies: identify a candidate gene and test its association with the disorder (in autism case: ones which play role in brain dev or neurotransmitter function) 2. Whole-genome studies
49
How come its hard to find specific genes responsable for ASD?
Due to genetic etiology in autism being heterogeneous
50
What are the structural neurobiological findings in terms of ASD etiology?
* overgrowth of cerebral gray and white matter -> larger head circumference over the first year of life * Structural abnormalities in the cerebellum -> social cog, language, executive functioning etc. -> may contribute to rapidly shifting attention from one stimulus to another
51
What are the functional neurobiological findings in terms of ASD etiology?
* Atypical patterns of connectivity (blood network) -> including in default mode network
52
What is the default mode network?
* active when individual not focused on external world and brain at wakeful rest focusing on internal tasks * hypothesized to be part of higher order social cog process lie ToM