Synteny
Two or more genes located on the same chromosome and are physically linked
Genetic Linkage
Genes close together on a chromosome tend to be transmitted as a unit, which influences inheritance patterns
Recombinant Cells
Haploid cells containing a unique combination of alleles not found in original parent chromosomes
Genetic Mapping
Performed to determine linear order of linked genes along same chromosome
The ____ two loci are from one another, the greater the chance crossover will occur
further
____ skews two factor crosses (instead of 9:3:3:1 ratio, 15.6:1:1.4:4.5 ratio observed, with most being heterozygous)
Linkage
____ impacts frequency of recombination
Map distance between loci
In triple cross, non-recombinant individuals have 2 dominant or 2 recessive traits, recombinant have one dominant and one recessive trait
Chi Square Analysis Steps
- Propose null hypothesis
- Calculate expected
- Apply chi square formula
- Interpret calculated chi square value to determine if two genes are linked (higher value = more likely)
Positive Interference
Phenomenon of first crossover decreasing the probability of another
