Module 6: Section 1 Flashcards

(46 cards)

1
Q

gastrointestinal system

A

a continuous series of hollow muscular tubes that extends from mouth -> anus
- movement of muscles and release of secretions allows for digestion and absorption of food

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2
Q

structures/organs of gastrointestinal system

A
  • nasal passages
  • mouth
  • salivary glands
  • esophagus
  • liver
  • stomach
  • gallbladder
  • pancreas
  • small intestine
  • colon
  • rectum
  • anus
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3
Q

main role of digestive system

A

take food and drinks consumed and transfer nutrients, water and electrolytes into body

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4
Q

5 stages of nutrient breakdown

A

1) ingestion
- physical act of eating
2) digestion
- breakdown of food into small molecules that can be absorbed
3) absorption
- movement of nutrients from digestive tract into circulatory system
4) distribution
- movement thru circulatory system for delivery to tissues/cells
5) usage
- movement of nutrients into cells fro metabolism or anabolic processes

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5
Q

what are the 4 basic digestive processes?

A

1) motility
2) secretion
3) digestion
4) absorption

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6
Q

digestive processes: motility

A
  • muscular contractions that mix/propel contents of digestive syst.
  • SM cells in dig. syst. have constant level of contraction/tone to prevent too much stretching of walls and keep pressure on contents
  • propulisive movements push contents forward
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7
Q

what does rate of movement in dig. syst determined by?

A

what segment of the digestive system it’s in

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8
Q

what do mixing movements help with

A

mixing the food w/ digestive enzymes and promote absorption by making sure all of it makes contact with walls of dig. syst

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9
Q

what digestive organs use skeletal muscle

A
  • top of esophagus
  • mouth
  • external anal sphincter
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10
Q

digestive processes: secretion

A
  • excocrine galnds that secrete dig juices into digestive tract lumen
  • contents of juices changes in diff parts
  • each part also secretes a unique mixture of enzymes, bile salts and mucus
  • secretions are reabsorbed after done their job
  • endocrine cells are present to secrete gastrointestinal hormones into blood
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11
Q

what determines contents of dig juices

A
  • regional function
  • but all contain electrolytes and water
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12
Q

what do gastrointestinal hormones do

A

control motility and exocrine gland secretion

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13
Q

where do secretory cells get their water and raw materials from?

A

plasma

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14
Q

digestive processes: digestion

A
  • the biochemical process of enzymatic breakdown of foods that are structurally complex into small absorbable units
  • each of the 3 biochemical families of food undergo diff processes
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14
Q

what are majority of carbs ingested as?

A

polysaccharides

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15
Q

polysaccharides

A

complex carbs consisting of many glucose molecules
- plant based ones are mainly starches (meats have polysaccharide glycogen)

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16
Q

what are some carbs ingested as?

A
  • disaccharides
    – eg, sucrose and lactose
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17
Q

during digestion, what happens to starch, glycogen and disaccharides?

A

broken down into monosaccharides (only they can be absorbed)
– mainly glucose w/ some fructose and galactose

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18
Q

monosaccharide

A

simple sugar
- eg, glucose

19
Q

what are dietary fats normally consumed as?

A

triglycerides

20
Q

triglycerides

A

free fatty acids attached to a glycerol molec

21
Q

what happens to triglycerides during digestion?

A

they are broken down by releasing 2 fatty acids
- leaves a monoglyceride ( a glycerol molec with 1 fatty acid attached)
- both free fatty acid and monoglyceride can be absorbed

22
Q

where does most absorption occur?

A

small intestine

23
Q

where is digestion completed?

A

small intestine

24
what do the small absorbable units in digestion produce?
- water, vitamins and electrolytes that move from digestive tract lumen to blood and lymph
25
digestive tract walls major layers
- mucosa - submucosa - muscularis externa - serosa
26
mucosa
- innermost layer - lines luminal surface - surface is highly folded to increase surface area -- little folding in esophagus but lots of folding in small intestine
27
submucosa
- thick - made of CT that supports mucosa - provides distensibility and elasticity to dig tract - has larger blood and lymph vessels that send smaller branches to mucosa and outer layers - has submucosal plexus
28
submucosal plexus
network of nerves
29
muscularis externa
- SM layer around submucosa - has 2 muscle layers -- inner circular and outer longitudinal -- cause propulsive and mixing contractions - between the 2 layers theres another nerve network -- myenteric plexus
30
what do contractions in inner layer of muscularis externa cause
- contractions in inner layer decrease lumen diameter
31
what do contractions in outer layer of muscularis externa cause
shortens tube
32
myenteric plexus
along with hormones and local chemical mediators.. - it helps to regulate local gut activity
33
serosa
- outer CT layer - covers dig tract - thru most of dig tract, serosa is continuous with mesentery - helps suspend dig organs from inner wall of abdominal cavity -- but still allows movement fro mixing and propulsion
34
what are the 4 regulatory factors that regulate dig syst
- autonomous SM function - intrinsic nervous plexus - extrinsic autonomic nerves - gastrointestinal hormones
35
what does autonomic NS influence?
motility and secretion - by modifying activity of enteric NS, regulating gastrointestinal hormone secretion, and some direct innervation of SM and glands
36
sympathetic innervation vs parasympathetic
sympathetic- tends to slow down dig tract contractions and secretions parasympathetic- increase SM cell contractility and promotes digestive juice secretions and hormones
37
what is unique to parasympathetic nerve supply in dig syst?
post ganglionic parasympathetic nerve fibers are a part of intrinsic NS
38
intrinsic nerve plexuses (aka enteric nervous system (ENS))
- submucosal plexus and myenteric plexus - primary purpose is self-regulation but it receives significant input from ANS
39
ENS functions on dig tract
- sensory neurons receive info on local stimuli - other nerves will innervate smooth muscle cells, exocrine glands and endocrine glands -- effects motility and sec from fig juices
40
what is is ENS connected by?
interneurons
41
slow wave potentials
rhythmic electrical activities in SM cells that regulate motility - spontaneous changes in membrane potential - originates from non-contractile interstitial cells of Cajal (ICC)
42
where are non-contractile interstitial cells of Cajal (ICC) located?
boundry of circlar and longitudinal muscle layers
43
are slow waves action potentials?
NO - so they cannot induce contractions
44
what happens to membrane potentials of SM cells?
oscillates towards and away from threshold - if it gets to threshhold at peak of depolarization they trigger a series of action potentials causing contraction
45
can slow wave potentials move between cells?
yes because of gap junctions - they can also act as functional syncytium and contract as a unit