1
Q
10q deletion
A
small cell astrocytoma (>90%)
- these also have EGFR amplification
2
Q
22q deletion
A
ATRT
DiGeorge
Meningioma
3
Q
i17q
A
medulloblastoma
4
Q
Myc amplification
A
medulloblastoma (poor prognosis)
5
Q
meningioma assd deletions
A
22q (most common), 1p, 14q
6
Q
IDH1 mutation
A
favors secondary GBM over de novo
7
Q
70% of small cell GBMs have
A
EGFR mutation
8
Q
most common mutation in GBM
A
loss of ch 10
