GABA-b agonist
Baclofen
glutamate receptor antagonist
Riluzole
Alpha-2 agonist
Tizanidine
works as antagonist at Kaninate and NDMA receptors, possibly inhibits Na+ channels and GCPRs
Riluzole
Tx ALS
riluzole
if have liver failure (checking transaminase levels), dont use ___.
It has a rare hepatotoxicity effect, also N/V
riluzole
use ___ to reverse some of riluzole’s clinical effects to have short improvement in median survival
pertussis toxin
which two drugs are used to tx spasticity?
baclofen and tizanidine
how does baclofen work?
loss of spinal motor nerve inputs from cortex
alpha 2-adrenergic auto receptor agonist?
tizanidine