MPox

Question 1

How is MPox spread?

Answer 1

skin to skin (when lesions present)
contact with body fluids
respiratory droplets

Question 2

Mpox incubation period

Answer 2

5-21 days

Question 3

Mpox look back period

Answer 3

21 days

Question 4

Which clade of Mpox is associated with more severe disease?

Answer 4

Clade 1

Question 5

How is Imvanex given as PEP?

Answer 5

Single dose within 4 and up to 14 days (if risk of severe illness) of exposure

Question 6

What is the imvanex dosing sechedule?

Answer 6

Either 0.5ml SC/IM or 0.1ml ID
2 doses, min 28 days apart

Question 7

Who should not have ID imvanex?

Answer 7

CD4 < 200 or risk of keloid scarring

Question 8

Who should only have a single dose of imnavex?

Answer 8

Previously received live smallpox vaccine in 1970s

Question 9

Who is recommended to receive imnavex?

Answer 9

GBMSM
Occupational exposure risk

Question 10

What treatment options are available for severe Mpox?

Answer 10

Tecoviromat
Cidofovir
Brincidofovir

Question 11

How long should you isolate with mpox?

Answer 11

Until all scabs have fallen off and fresh skin seen beneath
and
Fever free