Regarding coagulation cascade, extrinsic pathway/ intrinsic pathway is primarily activated by
Extrinsic pathway : Tissue factor / vascular injury
Intrinsic pathway : contact activation with negatively charged surface
Lifespan of mature erythrocytes
120 days
Na+ / K + AtPase pump is an
Antiporter
Lifespan of platelets
10 days
Resting membrane potential of a neuron + threshold potential
Resting = -70mv
Threshold potential = -55mv
Where glycoprotein hormone eryhthropoietin is produced
90 % kidney ( peritubular complex)
10% liver and other organs
Erythropietin secretion increased when
Hypoxia / anemia
Increase pathological secretion in polycystic kidney disease and renal cell carcinoma
Neuronal action potential depo and repo
Depolarization Na influx
Repolarization K+ efflux
Effect of Na/K pump on Na and K
3 Na+ out of cell
2 K+ in
Poiseuilles law in tube flow
R= (8VL) / ( pie r4)
R= resistance to flow provided by tube
V= viscosity of fluid flowing
L= length of tube
Parasympathetic preganglionic neurons run in which cranial nerves
III, VII, IX, X
