1st line Tx in RRMS
IFN, GA, Teriflunamide, DMF
2nd line Tx in RRMS
Fingolimod, NZ, ALZ
3rd line Tx in RRMS
Cyclophosphamide
1st line Tx in PPMS
Ocrelizumab
Tx of acute relapse of MS
IV methyl prednisolone
Tx of urinary incontinence in MS
Oxybutinin
Cut off value of urinary residual to give oxybutinin in MS
Less than 100 mls
Tx of fatigue in MS
Modafinil, amantadine
Tx of Rapidly evolving severe RRMS
Natalizumab
Tx of RRMS refractory to IFN with high disease activity
Natalizumab
Tx of 2ary progressive MS
Betaferon
Tools used for clinical assessment of MS severity
. Expanded disability stautus scale
(EDSS)
. MS Functional Composite [MSFC]