5 factor categories that can cause candidsis
physiological
trauma
haematological
iatrogenic
endocrinological
physiological factors for oral candidosis
pregnancy
age
saliva flow
trauma factors for candidosis
cellular immunodeficiency
neutropenia
iatrogenic factors for oral candidosis
antibiotics
catheters
surgery
endocrinological factors for candidosis
diabetes
addison disease
organisms that causes candidosis
and 3 virulence factors of it
candida albicans
hyphe, adhesins, hydrolytic enzymes
4 key stages of biolfilm formation
adhesion
colonisation
accumulation to form complex commuity
dispersal
how would you test for candida albicans and suggest a lab identification method
take a swab and culture the swab content’s on Sobouraud’s Agar and if present candida will present as white creamy colonies
lab testing - germ tube formation
PCR
example azole and mechanism
fluconazole
work by indirectly targeting th ergosterol in the fungi cell wall by interrupting the activity of the enzyme that produces it - 14 alpha demethylase
FUNGISTATIC
example polyene antifungal and mechanism of action
nystatin
directly target the ergosterol and cause perforation and leakage of intracellular contents
FUNGICIDAL
higher virulence but less well tolerated
example echinocandins and action
micafungin
FUNGICIDAL
3 classess of antifungals
azoles
polyenes
echinocandins
2 year with caries in all upper incisors and 6s
pattern of caries here
nursing bottle/early childhood caries
explain pattern and distribution of decay in nursing bottle/early childhood caries
why are some teeth not in the pattern?
lower incisors are spared from decay as they are physically protected by the nursing position of the child’s tongue - the artifical nipple of bottle rests against the palate, while tongue is extended over the lower incisors
maxillary incisors - 1st to experience the cariogenic challenge and suffer the longest cariogenic attack because of early eruption
if habit continues, other teeth (mandibular canines and all 6s) will be subjected to the cariogenic challenge in sequence of eruption
5 causes of nursing bottle/early childhood caries
fluoride regime for 2 year old with high caries risk in dental setting
4 brushing instructions for high caries risk 2 year old
ED# in 8 year old boy
most important emergency tx
aim to retain vitality of any damaged or displaced tooth by protecting exposed dentine by means of an adhesive dentine bandage
9 signs/symptoms to track progression of trauma (things on trauma stamp)
4 radiographic signs of non-vital tooth
peri-apical radiolucency
internal inflammatory resorption
external inflammatory resorption
ankylosis
child who has history of trauma is continuing to play active contact sports (rugby) what should you do
provide him with a mouthguard
5 signs digit sucking habit
proclined upper incisors
retroclined lower incisors
anterior open bite or incomplete open bite
unilateral posterior cross bite
narrowed upper arch
how does thumb sucking affect posterior dentition
pt thumb and digits are positioned in the mouth in such a way that they result in the mandible to drop open
sucking action initiaited by the muscular forces in the cheek’s narrows the maxillary arch - causing posterior cross bite
4 methods of preventing/stopping a digit sucking habit