MSK

Question 1

15 y/o male presents with 4 month history of growing lump on posterior aspect of his right thigh, extremely painful over last two weeks

radiograph shows lytic lesion in diaphysis of the right femur with an ‘onion skin’ appearance.

likely diagnosis?

Answer 1

Ewing’s sarcoma

malignant tumour that occurs most frequently in diaphysis of the pelvis and long bones

Question 2

describe osteoma

Answer 2

benign overgrowth of bone

typically in skull

Question 3

A 30-year-old man with a history of mitral valve prolapse, recurrent pneumothorax, lower back pain secondary to scoliosis and pectus excavatum is considering starting a family. Given the likely diagnosis, what is the mode of inheritance of this condition?

Answer 3

Patient has Marfan’s syndrome

autosomal dominant connective tissue disorder

Question 4

features of Marfans syndrome

Answer 4

• tall stature
• high arched palate
• pectus excavatum
• scoliosis
• dilation of aortic sinuses, mitral valve prolapse
• repeated pnuemothoraces
• upward lens dislocation

Question 5

‘Can’t see, pee or climb a tree’

Answer 5

reactive arthritis

treated with NSAIDS

Question 6

what deformity is a classic finding in psoriatic arthropathy and may be seen in rheumatoid arthritis

Answer 6

pencil in cup deformity

Question 7

what might be found on X-ray in a patient with ankylosing spondylitis

Answer 7

subchondral erosions

sclerosis

squaring of lumbar vertebrae

Question 8

27 y/o female presents with

• painful genital ulceration
• had recurrent attacks for past four years
• mouth ulcers slow to heal
• PMH of thrombophlebitis two years ago

likely diagnosis?

Answer 8

Behcet’s syndrome

• complex multisystem disorder associated with presumed autoimmune mediated inflammation of arteries and veins