Mucosal Administration

Question 1

What are the potential targets for lung diseases?

Answer 1

Aveolar macrophages

Epithelial cells

Question 2

What is the optimal size for drugs for for lung administration?

Answer 2

1-5 micrometers

Question 3

What nanoparticles used in pulmonary drug delivery?

Answer 3

• Liposomes
• Polymeric nanoparticles
• Solid lipid nanoparticles
• Protein nanoparticles

Question 4

What 3 main properties for passive targeting for pulmonary drug delivery do we act upon?

Answer 4

Size
Charge
Surface properties

Question 5

What cells in the lung can you actively target?

Answer 5

Alveolar macrophages

Bronchial epithelial

Question 6

What receptors on alveolar macrophages can you target?

Answer 6

Mannose