Muscle

Question 1

What happens when muscle is injured (necrosis & regeneration)?

Answer 1

1. damage => microfibre necrosis
2. Inflammation & phagocytosis
3. Hypercontration of myofibrils (> stop necrosis/cell death from spreading to rest of cell)
4. revascularisation
5. Satellite cells activate & proliferate
6. fusion of myoblast & myotubules
7. re-innercation
8. growth & maturation

Question 2

What are satellite cells and their function?

Answer 2

muscle-specific stem cells
> facilitate post-natal growth & regeneration:
- activate, proliferate, differentiate & fuse into yofibres