mychophenolate mofetil

Question 1

MOA of mycophenalate mofetil

Answer 1

• inhibits inosine monophosphate dehydrogenase (inhibits purine synthesis)

Question 2

mycophenalate mofetil requires _____ for cleavage into active form.

Answer 2

gastric acidity

Question 3

mycophenalate mofetil is pregnancy category____

Answer 3

D!, absolute contraindication

Question 4

Most common AE’s of mycophenalate mofetil?

Answer 4

GI upset

Question 5

What lab monitoring should be done for patient on mycophenalate mofetil?

Answer 5

Initially: CBC w/ diff, BMP, LFTs, Hep B, Hep C, TB screen, and pregnancy test

• then at 2-4 weeks recheck CBC w/ diff, BMP and LFTs
• when stable, continue to monitor every two to three months