Virulence factor of M. Tuberculosis. Gove MOA
Sulfatide - prevents lysosome and phagosome fusion
Cord factor - inhibits chemotaxis
Indication of primary tuberculosis infection
Ghon complex
Indication of secondary tuberculosis infection
Apex
Extrulmonary TB at the vertebrate
Pott’s disease
Gold standard for dx of TB
Sputum microscopy
Culture media for M. Tuberculosis
Lowenstein Jensen medium
Inhibits mycolic acid synthesis
Isoniazid
Inhibits DNA dependent RNA polymerase
Rifampicin
Inhibits arabinogalactan synthesis
Ethambutol
2nd line anti-TB
Streptomycin Polypeptides Fluoroquinolones Thioamides Cycloserine P-aminosalicylic acid
Causes TB in AIDS patient
M. Aviun intracellulare
Yellow bacillus
M. Kansaii
Hansen’s bacillus
M. Leprae
Koch’s bacillus
Mycobacterium tuberculosis