Direct stimuli
cerebral cortex (anticipation & fear) Sensory organs (signs, odor, pain) vestibular
Indirect stimuli
1st activation CTZ then the vomiting centre
1) signals from the stomach & small intestine (vagal)
Direct emetogenic compounds
Pre-preg risk HG
younger, migraines, asthma, pre-exisitng diabetes, hypertrophy, h.pylori
Pregnancy risk of HG
Gestational trophoblastic, female, multifetal assistive