NALD

Question 1

pathophysiology

Answer 1

insulin receptors are less responsive
increased fat storage and decreased fatty acid oxidation

Question 1

steatosis

Answer 1

increased syntheiss and uptake of free fatty acids
causing fat droplets to form in hepatocytes

Question 2

what might happen to hepatocyes

Answer 2

theyll swell and push nuclei to the edge of the cell

Question 3

what does the liver look like

Answer 3

large
soft
yellow and greasy

Question 4

steatohepatitis

Answer 4

steatosis plus inflammatio.

Question 5

action of stellate cells in chronic

Answer 5

lay down fibrotic tissue

Question 6

non alcoholic lab results

Answer 6

increased alt more than ast

Question 7

alcoholic lab results

Answer 7

more raised ast than alt

Question 8

investigations

Answer 8

ultrasound, ct or mri to look for fatty infiltrates

Question 9

how to confirm diagnosis and assess severity

Answer 9

biopsy