Neoplasm conditions (new)

Question 1

name these cell types - in which condition is it found

Answer 1

REED-STERNBERG CELL = abnormal germinal centre B cell

EOSINOPHILS (pink-staining cytoplasm) - attracted by malignant cells

Found in HODGKIN’S LYMPHOMA

Question 2

what are lymphomas and what are the main types

Answer 2

Lymphoma = cancer developing from lymphocytes, more often B cells

1. Non-Hodgkin’s lymphoma
2. Hodgkin’s lymphoma (15%)
3. Multiple myeloma (from plasma cells, i.e. effector B cells)
4. Lymphoproliferative diseases

Question 3

name the major risk factor for Hodkin’s lymphoma

Answer 3

Epstein-Barr Virus infection - infects lymphocytes

Question 4

describe the presentation of Hodgkin’s lymphoma

Answer 4

1. enlarged lymph nodes, e.g. cervical, axilla, groin
2. B symptoms: fever, night sweats and weight loss