nervous Flashcards

(117 cards)

1
Q

the prosencephalon includes which parts
a) telencephalon
b) mesencephalon
c) metencephalon
d) myelencephalon

A

A and diencephalon- forebrain

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2
Q

the prosencephalon includes which parts
a) pons
b) cerebellum
c) cerebral cortex
d) basal nuclei
e) thalamus
f) hypothalamus
g) cerebral peduncles
h) midbrain
i) medulla oblongata

A

C, D, E, F
The telencephalon develops into the cerebrum, which includes the cerebral cortex, underlying white matter, and the basal nuclei (also known as basal ganglia).
The diencephalon develops into the thalamus and hypothalamus (as well as the epithalamus and subthalamus
and the limbic system

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3
Q

the mesencephalon includes the
a) pons
b) cerebellum
c) cerebral cortex
d) basal nuclei
e) thalamus
f) hypothalamus
g)cerebral peduncles
h) midbrain
i) medulla oblongata

A

G, H- midbrain including tectum, tegmentum, cerebral peduncles

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4
Q

the metencephalon includes what?
a) pons
b) cerebellum
c) cerebral cortex
d) basal nuclei
e) thalamus
f) hypothalamus
g)cerebral peduncles
h) midbrain
i) medulla oblongata

A

A, B

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5
Q

the rhombencephalon includes:
a) telencephalon
b) mesencephalon
c) metencephalon
d) myelencephalon

A

C (pons, cerebellum) and D (medulla oblongata)

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6
Q

which cranial nerves come from the forebrain?

A

olfactory and optic

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7
Q

which cranial nerves come from the midbrain

A

oculomotor, trochlear

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8
Q

which cranial nerve comes from the pons

A

trigeminal

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9
Q

which cranial nerve runs through the foramen magnum?

A

part of the accessory nerve:
The accessory nerve, has its origin in the medulla oblongata and also in the cervical spinal cord. The cranial roots have their cell bodies in the caudal portion of the nucleus ambiguus of the medulla oblongata.
Lateral to the medulla, they join the axons of the spinal roots, which enter the cranial cavity via the foramen magnum. Within the cranial cavity the spinal part of the accessory nerve lies on the ventrolateral surface of the medulla before joining the cranial roots to form the accessory
nerve.
In addition to dorsal and ventral roots, the first seven (sometimes eight) cervical segments have rootlets that emerge midlaterally from the spinal cord and join to form the spinal root of the accessory nerve
The axons in the spinal roots are contained in the external branch of the accessory nerve, which leaves the cranial cavity with the vagus and glossopharyngeal nerves through the jugular foramen (inner skull hole) and through tympanooccipital fissure

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10
Q

in the spinal cord, where do the afferent neuron arise from?
a) ventral horn
b) dorsal horn
c) dorsal funiculus
d) venral funiculus

A

B- grey matter- afferent is incoming, sensory information
grey matter is central and white matter is peripheral in the cord

dorsal is both somatic and visceral sensory
somatic is medially located
visceral is laterally located

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11
Q

in the spinal cord, where do the efferent neuron arise from?
a) ventral horn
b) dorsal horn
c) dorsal funiculus
d) venral funiculus

A

A- grey matter- effect, motor

both somatic and visceral autonomic

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12
Q

what is the role of white matter in the spinal cord?

A

Spinal cord white matter is formed by concentrations of myelinated and nonmyelinated axons. Within white matter,
there are afferent axons, which enter the spinal cord through dorsal roots, efferent axons, which exit the spinal cord through
ventral roots, and axons that compose pathways that convey information cranially and caudally in the spinal cord. Cranially and caudally projecting axons conveying information from one location to another typically have a common function and travel together in the white matter. Collectively,
the related axons are identified as a tract or fasciculus. Tracts are named for their origin and termination (e.g., spinothalamic
and vestibulospinal).

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13
Q

the white matter of the spinal cord is made up of:
a) 3 horns- dorsal, ventral and middle
b) 3 funiculi- dorsal, lateral and ventral
c) 3 trabeculae- dorsal, ventral and middle

A

B

positioned superficially in the spinal cord. It features packed myelinated axons. Nonmyelinated axons are also present in white matter, as are oligodendrocytes, astrocytes, and blood vessels (these vessels are less dense than those in gray matter).
The funiculi are composed of ascending and descending nerve fibers many of which are
grouped into bundles (fasciculi or tracts)
o These tracts connect the brain and interconnect the various spinal segments of the cord
E.g. rubrospinal tract, ventral spinocerebellar tract etc.

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14
Q
  1. Which funiculus primarily carries fine touch, vibration, and conscious proprioception?
    A. ventral funiculus
    B. Lateral funiculus
    C. dorsal funiculus
    D. Central gray matter
A

C

dorsal funiculus = precise sensory (touch, vibration, proprioception).

Lateral funiculus = mixed sensory (pain, temperature, proprioception) + motor control.

ventral funiculus = mostly motor + crude sensory.

The dorsal funiculus – consists essentially of ascending tracts mainly involved in proprioception
The lateral funiculus – contains both ascending (proprioception, touch, pressure, temperature and pain pathways) and descending (motor
pathways) tracts
The ventral funiculus – contains only descending motor tracts.

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15
Q
  1. The lateral corticospinal tract, which controls voluntary movement, is located in the:
    A. dorsal funiculus
    B. Lateral funiculus
    C. ventral horn
    D. Central canal
A

B

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16
Q

which spinal nerves have ganglions? dorsal or ventral or both?

A

Dorsal root - afferent (sensory) fibres whose cell bodies are clumped together to form a
visible swelling — the DORSAL ROOT GANGLION
o Ventral Root - efferent fibres emanating from the ventral horn of the gray matter
These two roots join peripherally to the dorsal root ganglion to form the mixed spinal nerve that leaves the canal through the IVF

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17
Q

does the spinal cord extend further caudally at birth or at maturity?

A

at birth
At birth, the canine spinal cord extends into the sacrum. Following postnatal development, the spinal cord terminates in
the caudal lumbar region. Overall, the vertebral column outgrows the spinal cord in length; however, the degree of elongate
growth of spinal cord segments is regionally variable

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18
Q

where does the most cranial spinal cord nerve exit the central nervous system?

A

lateral vertebral foramen, located in the dorsal arch of the atlas.

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19
Q

are the nerves that make up the cauda equina surrounded by meninges?

A

yes- tightly

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20
Q

Within the vertebral canal, an epidural space separates spinal cord dura mater from the periosteum lining the canal, except where?
a) dorsally level with c1
b) ventrally, level with c1 and c2
c) foramen magnum- brachial plexus, where it is fused to the periosteum circumferentially
d) dorsally level with c1 and c2

A

B it is fused with the periosteum

There is no epidural space in the cranial cavity, because cranial dura mater doubles as periosteum. It originates embryologically as a double layer, and at certain locations it splits into an outer periosteal layer and an inner layer that forms partitions between
parts of the brain. A venous sinus is generally present where the layers separate

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21
Q

how fat does the meningeal/ dural sheath extend along the nerve root

A

At an intervertebral foramen, meningeal sheath fibrous tissue becomes continuous with epineurium and perineurium
of spinal nerves. Also, dura mater merges with periosteum. In the lumbosacral region, fibrous bands extend from the spinal cord dura mater to the floor of the vertebral canal. The bands often accompany spinal roots and attach near intervertebral
foramina.

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22
Q

what is the denticulate ligament?

A

Pia mater collagen is bilaterally thickened along the lateral surface of the spinal cord, forming a denticulate ligament. Denticulate
ligaments have lateral extensions that traverse the subarachnoid space and attach to dura mater, thereby suspending the spinal cord in cerebrospinal fluid within the subarachnoid space.

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23
Q

what is th embryological origin of the ventricular system of the brain?
a) ectoderm
b) neural tube
c) mesoderm
d) endoderm
e) neural crest

A

B

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24
Q

what is the tela choroidea

A

The tela choroidea is the thin, highly vascularised, loose connective tissue portion of pia mater that gives rise to the choroid plexus. Thus, it is basically the lamina propria of the ependyma and lies directly adherent to it, without any tissue in between the two. At one region along the wall of each ventricle, nervous tissue is absent so that pia mater contacts ependyma. The combined tissue, called tela choroidea, forms part of the floor of each lateral ventricle and the roof of the third and fourth ventricles. Tela choroidea plus a plexus of capillaries gives rise to choroid plexus.

At one region along the wall of each ventricle, nervous tissue is absent so that pia mater contacts ependyma. The combined tissue, called tela choroidea, forms part of the floor of each lateral
ventricle and the roof of the third and fourth ventricles.
- tela choroidea + a plexus of capillaries = choroid plexus.

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25
fill in the blanks
green- mesencephalic aqueduct orange- (ventral horn (temporal), lateral ventricle purple- third ventricle
26
what is this
mesencephalic aqueduct
27
what is the normal rate of csf production in dogs? a) 1ml/min b) 3ml/min c) 0.05ml/min d) 0.01ml/min
C or 3ml/hr Feline --> 0.017 mL/min or 1 mls/hr Hu --> 0.5 mL/min - Rate of production is independent of blood hydrostatic pressure but is influenced by osmotic pressure of blood (hypertonic solutions in the blood reduce rate of formation - you can give hypertonic NaCl to reduce ICP) - Rate of production also independent of pressure of CSF in the ventricular system
28
where does lymph drain to drom the brain?
into the ventricular system, the central nervous system lacks lymph vessels
29
can csf and extracellular fluid mix?
Cerebrospinal fluid is separated from extracellular fluid of nervous tissue by glial limiting membrane and either pia mater or ependyma. Solutes can be exchanged between the two fluid compartments, and cerebrospinal fluid is normally augmented by flow of extracellular fluid from nervous tissue.
30
explain the pathway of the flow of csf
Cerebrospinal fluid flows from the lateral ventricles, through interventricular foramina, into the third ventricle, and, through the mesencephalic aqueduct, into the fourth ventricle. From the fourth ventricle, fluid flows into the subarachnoid space, through bilateral recesses and apertures. A very small amount of fluid from the fourth ventricle flows into the central canal and, ultimately, the terminal ventricle of the spinal cord.
31
how does csf return to the blood?
Two major drainage routes for return of cerebrospinal fluid to blood are arachnoid villi and lymphatics associated with nerves. There is considerable fluid drainage associated with the optic and olfactory nerves. minimal retruns through venules in the subarachnoid space
32
what is the relationship between the lumbosacral nerve segments and their corresponding vertebrae?
Caudal lumbar, sacral, caudal region--> segments lie progressively cranial to their respective vertebra
33
what is the relationship between the cervical nerve segments and their corresponding vertebrae?
- Initial Cervical Region - The first cervical segment lies within the corresponding vertebra - Caudal cervical through cranial thoracic region - Segments are positioned cranial to their respective vertebrae - Thoracolumbar region - Segments lie within their corresponding vertebrae
34
where does th espianl cord end in dogs and cats?
o End of the spinal cord - Ca – L5/L6; Fe – L6/L7 o Eq – S2 o Ru and Su – L6
35
which nerve innervates the trapezius mm?
accessory
36
which nerve innervates the omotransversarius mm?
accessory
37
which nerve innervates the brachiocephalicus and rhomboideus mm?
not accessory?
38
which nerve innervates the biceps mm?
musculocutaneous (also brachialis mm) also biceps reflex
39
which nerve innervates the triceps mm?
radial also triceps reflex
40
which nerve from the brachial plexus extends laterally around the caudal aspect of the humerus? a) axillary b) median c) radial d) ulnar
C- passes close to the triceps which it innervates. the others remain medial also inntervate the extensors, which are lateral on the elbow - Radial nerve (C7-T-2) – largest nerve of the brachial plexus o Supplies the extensors of the elbow, carpal and digital joints, triceps, supinator, brachioradialis, and abductor pollicis longus muscles -- ALL CAUDOLATERAL MUSCLES!
41
which brachial plexus nerves inntervates the flexors of the carpus and digits?
median and ulnar
42
which spinal nerve segments make up the sciatic nerve generally?
L6, 7, s1
43
which muscles of the proximal thigh does the sciatic nerve innervate?
biceps femoris, semimembranous, semitendinous also others through the common peroneal and tibial nn.
44
which pelvic limb nerve is important for the flexor reflex?
sciatic nerve largest nn in the body
45
The axillary nerve innervates the? a) extensors of the shoulder b) flexors of the shoulder c) flexors of the elbow d) extensors of the elbow
B mm. teres major and deltoideous - Cranial lateral cutaneous brachial nerve
46
what is the function of the femoral nerve (2)? a) extensors of the pelvic limb b) flexors of the pelvic limb c) ancillary flexor of the hip d) bladder control
A, C
47
which muscles does the proximal femoral nerve pass through?
psoas mm Exits through the psoas muscles to reach a gap between the dorsocaudal corner of the flank and the psoas muscles (femoral canal). -It is accompanied by the femoral artery and vein and runs between the sartorius and pectineus. -Ends within the quadriceps femoris - Innervates - extensors of the limb and ancillary flexor of the hip - Damage to this nerve is bad – the quadriceps muscle would be paralysed and the stifle joint cannot be fixated, the limb cannot support weight
48
where does the phrenic nerve originate?
- Cervical Ventral Rami - PHRENIC NERVE - Formed by the 5th, 6th, and 7th cervical nerves, extending ventrally to enter the mediastinum between the first 2 ribs. - The right nerve utilizes the plica vena cavae in the last part of its course. - The left phrenic nerve lies in a similar plica from the entire left pleural sheet of the mediastinum - The nerve ramifies in the diaphragm - Exit the neuroforamen CRANIAL to the cervical vertebrae
49
which nerves are important for urine retention
hypogastric and pudendal
50
whare does the hypogastric nerve originate
L1-4
51
where does the pudendal nerve originate
s1-s2
52
How is urine retention controlled (nerves, receptors, action)
- detrusor m. relaxation --> HYPOGASTRIC nerve (beta-adrenergic) (L1-L4) - internal sphincter contraction -->HYPOGASTRIC nerve (alpha-adrenergic) (L1-L4) - external sphincter contraction --> PUDENDAL nerve (S1-S2)(nicotinic)
53
which nerves are important for urination?
hypogastric, pudendal and pelvic
54
where does the pelvic nerve originate?
S1-3
55
how is urination controlled (nerves, receptors, action)
parasympathetic: - internal sphincter relaxation --> inhibition of hypogastric input - external sphincter relaxation --> inhibition of pudendal input - detrusor m. contraction --> PELVIC nerve (S1-S3) (muscarinic ACh receptors)
56
where is the lesion if the bladder is hard and difficult to express
pons-L7. upper motor neuron bladder
57
where is the lesion if the bladder is flaccid and difficult to express?
S1-3. LMN bladder
58
where is cerebrospinal fluid produced? how is it produced?
choroid plexus (some from pial vessels and other parts of ependymal lining) secretion and ultrafiltration
59
what type of cells line the ventricles in the brain?
modified ependymal cells
60
which is false about the composition of CSF? a) higher k+ than plasma b) higher ca2+ than plasma c) lower Na+ than plasma d) higher protein than plasma
D Contains little protein -->blood-brain barrier (BBB) is impermeable for large molecules
61
which is false about the composition of CSF? a) relatively deficient in glucosa b) no red blood cells c) very low to no white blood cells d) lower K+ than plasma
D
62
which part of the midbrain are the colliculi attached to? a) tegmentum b) tectum c) mesencephalic aqueduct d) quadrigeminal cistern
B
63
which colliculus is connected to the lateral geniculate body, and responsible for part of the vision pathway?
rostral
64
the _____ colliculus is connected to the ______ geniculate body, and responsible for part of the auditory pathway
caudal colliculus medial geniculate body
65
which geniculate body is important for vision? medial or lateral
Lateral
66
which geniculate body receives acoustic fibres?
medial
67
the geniculate bodies are in the... a) hypothalamus b) tectum of the midbrain c) thalamus d) midbrain
C
68
the pineal gland is part of the a) thalamus b) epithalamus c) tectum d) quadrigeminal cistern
B
69
which is the lentiform nucleus
70
which is the claustrum and the caudate nucleus
71
?
hippocampus
72
hat is the main difference between the pyramidal tracts (corticospinal & corticobulbar) and the extrapyramidal system in motor control?
The pyramidal tracts carry UMNs directly from the cerebral cortex through the crus cerebri to innervate LMNs in the ventral horn or cranial nerve motor nuclei. In contrast, the extrapyramidal system provides indirect control by modulating and regulating the activity of ventral horn cells.
73
which are the lateral and medial geniculate nuclei
74
for the cranial nerves, are the motor nuclei dorsal or ventrally located
Nuclei of the cranial nerves - continuation of the four functional components of the spinal cord that compose the gray matter of the spinal cord - somatic/visceral afferent and somatic/visceral efferent MOTOR NUCLEI --> VENTRAL SENSORY NUCLEI --> DORSAL
75
patient circling to the left, absent menace in the right eye, abnormal postural reactions in the right thoracic and pelvic limbs. normal withdrawal reflexes in all limbs. where is the lesion?
left forebrain
76
a patient with seizures had a head turn towards the right, where is the lesion?
right forebrain turn towards the side of the lesion as a lesion on the right effects vision perception in the left eye. turn away from side they are blind on
77
which nerves are tested with the menace response?
optic facial - blink possible abducens and muscles of neck to move away
78
which of the following is not involved in the menace response? a) cerebellum b) thalamus c) medulla oblongata d) trigeminal nerve
D menace response tests a lot of areas, but lesions could happen in the visual pathway that also then effect the response depending on the mental status some won't respond or stop responding with repeated testing
79
which nerve is responsible for facial sensation?
trigeminal
80
if the patient has absent facial sensation on the left, where is the lesion?
right side, crosses over
81
if the patient is unconscious, were is the lesion?
brain stem- ascending reticular activating system brainstem also for Cardiovascular, respiratory, swallowing, voluntary excretion, vomiting, muscle tone and voluntary movement
82
where is the red nucleus? what is it important for? a) pons b) mid brain c) MO d) thalamus
midbrain for gait generation
83
what is the difference between decerebrate and decerebellate posture?
decerebrate- midbrain lesion- unconscious decerebellate- lesion in cerebellum, conscious leg position can be misleading
84
which muscles does the oculomotor nerve control?
-dorsal, medial ventral rectus and ventral oblique -levator palpebrae superioris- opens eyelid -iridial sphincter muscle- iris
85
which cranial nerves are tested with the PLR?
optic, occulomotor
86
a patient has unilateral strabismus (right eye looking laterally) and a reduced plr on the right but normal on the left (direct and indirect), the patient has a positive menace bilaterally, where is the lesion?
oculomotor nerve looking laterally as lost motor to medial rectus
87
what is special about the trochlear nerve compared to other cranial nerves?
the only one that arises dorsally in the midbrain, only one that crosses over
88
which nerve provides sensation to the inner nose and cornea?
ophthalmic branch of trigeminal nn.
89
how does sympathetic innervation reach the eye?
90
which nerves are important in the gag reflex?
IX, X, XI- nucleus ambiguus
91
with standard vestibular disease, the head tilt is usually which direction?
towards the lesion
92
a patient has a head tilt to the left, is falling to the left, has abnormal strabismus and nystagmus and abnormal postural reactions in the left limbs, where is the lesion
central vestibular- brain stem
93
a patient has a wide based stance and hypermetric gait and left sided menace deficits with normal vision, where is the lesion?
left cerebellar
94
a patient has a head tilt to the LEFT, is falling to the LEFT, has abnormal strabismus and nystagmus and abnormal postural reactions in the RIGHT limbs, where is the lesion
paradoxical vestibular- caudal cerebellar peduncle
95
a lesion in the cerebellum causes which clinical sign?(2) a) deficits in all four limbs or contralateral to the lesion b) deficits in all four limbs or ipsilateral to the lesion c) normal or increased spinal reflexes in all limbs d) ipsilateral menace deficits
B and D
96
a lesion where, would cause normal to increased spinal reflexes in all four limbs? a) cerebrum b) cerebellum c) brainstem d) c6-T2
A, B, C- UMN can also occur with thalamic or hypothalamic lesions
97
if a patient is bilaterally blind with a normal PLR, where is the lesion? a) optic nerve b) pre-tectal nucleus c) ciliary ganglions d) occipital lobe
D
98
with a unilateral lesion in the diencephalon (thalamus, hypothalamus) which side are the central nervous system signs affected and which side are the motor signs affected? a) CN are ipsilateral, motor are contralateral b) CN are ipsilateral, motor are ipsilateral c) CN are contralateral, motor are contralateral d) CN are contralateral, motor are ipsilateral
A
99
retrocolis and convergence retraction nystagmus are a sign of disease where? a) cerebrum b) midbrain c) cerebellum d) pons
B Dorsal midbrain Convergence-retraction nystagmus is a type of jerky eye movement where the eyeballs converge (turn inward) and then retract (pull back into the orbit), especially during attempted upgaze or when following a downward-moving object. Retrocollis is a type of torticollis (a condition causing neck muscle spasms) where the head is drawn backward due to repetitive muscle contractions in the neck, resulting in neck extension OPISTHOTONUS --> midbrain and rostral cerebellum lesions
100
with a unilateral lesion in the brainstem which side are the central nervous system signs affected and which side are the motor signs affected? a) CN are ipsilateral, motor are contralateral b) CN are ipsilateral, motor are ipsilateral or contralateral c) CN are contralateral, motor are contralateral d) CN are contralateral, motor are ipsilateral
B
101
With vestibular disease, which of these would indicate central vestibular disease? a) normal facial sensation b) ipsilateral postural reaction deficits c) horners d) vertical or positional nystagmus
B, D horners could be central or peripheral but having horners is rare with central vestibular and more common with peripheral vestibular Primary characteristics of peripheral vestibular disease are: - Symmetric ataxia without deficits in postural reaction - No paresis or loss of proprioception - Horizontal or rotatory nystagmus that DOES NOT change direction with different head positions - Quick phase is away from the side of the lesion
102
what autonomic functions does the facial nerve have?
parasympathetic to the lacrimal gland, 3rd eyelid gland, palatine and nasal glands taste on the rostral tongue
103
which test does not test the facial nerve? a) menace b) palpebral c) gag d) corneal
C
104
which nerves and segments are important for the perineal reflex in dogs and cats?
pudendal nerve and the S1–S3 spinal cord segments. sensory- pudendal motor from s1-s1 segments causing the anal sphincter to contract and often the tail to flex
105
which major nerves are tested in the withdrawal reflex of the thoracic limb?
loads- radial ulna, median and musculocutaneous
106
which major nerves are tested in the withdrawal reflex of the pelvic limb?
sciatic only THE SCIATIC NERVE INNERVATES NEARLY ALL FLEXOR MUSCLES IN THE PELVIC LIMB. withdrawal reflex assesses pretty much only the sciatic nerve!
107
which muscle innervates the biceps brachii, and is important for the myotactic reflex? which nerve segment is this?
musculocutneous (c6) c7-8 (t1)
108
which muscle innervates the triceps brachii, and is important for the myotactic reflex? which nerve segment is this?
radial (alnd all extensors) c7-8 (t1, 2)
109
which muscle innervates the quadriceps and is important for the patella reflex? which nerve segment is this?
femoral (L3), L4-5 (L6)
110
which muscle innervates the gastrocnemius, and is important for the myotactic reflex? which nerve segment is this?
tibial (part of sciatic) L6-7 (s1) does a lot of flexors in the hindlimb.
111
which muscle innervates the cranial tibial mm, and is important for the myotactic reflex? which nerve segment is this?
Peroneal (part of sciatic) L6-7 (s1) the peroneal does a lot of extensors muscles
112
if a lesion is in the cervical spine what neurological signs are expected?
nerve root signature*
113
if a lesion is in c6-T2 what neurological signs are expected?
114
if a lesion is in T3-L3 what neurological signs are expected?
115
if a lesion is in the lumbosacral region what neurological signs are expected?
nerve root signature*
116
where does the phrenic nerve arise from?
c5-7
117
which nerve passes through the inguinal ring?
genitofemoral (L3-4) Medial aspect of the thigh * Spermatic fasciae, scrotum and prepuce, CREMASTER MUSCLE * Inguinal mammary gland and its covering skin in the female