Neurogenetics

Question 1

Which codon is repeated in Huntington’s disease?

Answer 1

CAG

Question 2

How many repeats of CAG in the huntingtin gene is normal?

Answer 2

<27

Question 3

How many repeats of CAG in the huntingtin gene means someone will develop Huntonton’s disease?

Answer 3

40 or more

Question 4

Which chromosome is the huntingtin gene on?

Answer 4

4

Question 5

What pattern of inheritance does Huntington’s disease display?

Answer 5

Autosomal dominant

Question 6

What pattern of inheritance does Friedreich’s ataxia display?

Answer 6

Autosomal recessive

Question 7

Which codon is repeated in Friedreich’s ataxia?

Answer 7

GAA

Question 8

Which chromosome is the Friedreich’s ataxia gene on?

Answer 8

9

Question 9

How many GAA repeats in the FTX gene must a person have to develop Friedreich’s ataxia?

Answer 9

66 or more