Neurulation

Question 1

Neurulation

Answer 1

Neural plate rolls up to form the neural tube – driven by changes in cell shape

Question 2

Property of neuroepithelial cells

Answer 2

Neural plate neuroepithelial cells are polarised.

Question 3

What is on apical domain of neuroepithelial cells?

Answer 3

A band of F-actin is at the apical domain

Question 4

What happens when F-actin pulls tight? what interacts with it?

Answer 4

If this pulls tight, the cells are constricted at that edge and so change shape (imagine a purse string). - Many Molecules interact with F-actin to make it constrict.

Question 5

Folate

Answer 5

Changes in cell shape by folate which lead to changes in tissue shape.
As cellular apices constrict the tissue folds
Functions as a signal modifying cellular shape