FARMA CARDIO❤️ > nitratos > Flashcards

nitratos Flashcards

(20 cards)

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1
Q

mecanismo de acción de nitratos

A

favorecer la liberacion de ON en celulas musculares lisas

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2
Q

tipos de nitratos

A
  • nitroglicerina
  • nitropruziato
  • isosorbida
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3
Q

que hace el oxido nítrico?

A

regula la entrada de calcio desde afuera

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4
Q

en donde tienen mayor efecto los nitratos?

A

en vasos venosos

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5
Q

efectos CV de nitratos

A

disminuye
* precarga
* GC
* tensión en paredes ventriculares

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6
Q

cuál es la finalidad de usar nitratos?

A
  • disminuir demanda de O2
  • incrementar aporte de O2
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7
Q

usos de nitratos

A
  • estable
  • inestable
  • variante
  • IAM
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8
Q

vias de absorcion rapidas para nitratos

A
  • sublingual
  • transdérmica
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9
Q

que via de administración de nitratos requiere una dosis alta?
- que tipo de nitrato?

A
  • oral
  • isosorbida
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10
Q

EA de nitratos

A
  • mucha vasodilatación (cefalea, hipotensión, vértigo y taqui refleja)
  • taquicardia incrementa demanda de O2
  • tolerancia
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11
Q

como se podría evitar una taqui refleja?

A

con B bloqueadores (normalmente se combinan con nitratos)

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12
Q

como evitar la tolerancia de los nitratos?

A
  • tiempo sin parche
  • descansos de aprox 10 horas
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13
Q

interacciones medicamentosas de nitratos

A
  • sildenafil
  • poppers
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14
Q

que efectos podrían causar los nitratos con sildenafil?

A
  • hipotensión intensa
  • taquicardia
  • angina
  • fallecimiento
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15
Q

con que medicamento los poppers tendrían un efecto fatal?

A

viagra

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16
Q

cuando se pueden tomar los antianginosos?

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A
  • durante episodio
  • preventivo: px que siempre se sienten mal
17
Q

usos de nitroglicerina

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A
  • estable
  • inestable
  • ICc
18
Q

uso de isosorbide

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A

angina crónica

19
Q

riesgo de nitroprusiato

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A

libera cianuro

20
Q

1ra linea para angina estable

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A

nitroglicerina sublingual

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