drug class
nitrite
mechanism of action
vasodilation bc of relaxing smooth muscle, dilates coronary arteries = oxygen to ischemic myocardial tissue
indications
treatment and prevention of angina
contraindications
closed angle glaucoma, hypotension, severe head injury, ED drugs
adverse effects
headaches (usually go away w/ use), tachy, reflex tachy, postural hypotension, topical can cause dermatitis, tolerance may develop
routes and for what
oral (has large 1st pass effect), Iv for perioperative HTN, HR, ischemic pain, pulmonary edema assc. with MI, hypertensive emergencies