1
Q
Which of the following uses drosha?
siRNA
miRNA
piRNA
A
miRNA
2
Q
Which of the following uses ARGO2, Dicer, and RISC complex?
siRNA
miRNA
piRNA
A
siRNA and miRNA
3
Q
What is the end result of the siRNA pathway?
A
mRNA cleavage
4
Q
What is the end result of the miRNA pathway?
A
translational repression or mRNA decay
5
Q
What is the end result of the piRNA pathway?
A
Trans-P-oson silencing.
6
Q
Which of the following comes from a double stranded precoursor?
siRNA
miRNA
piRNA
A
siRNA
7
Q
Which of the following comes from a hairpin loop precursor?
siRNA
miRNA
piRNA
A
miRNA
8
Q
How do RNase H dependant ASOs (antisense oligonucleotides) work?
A
Single stranded ASO DNA molecules are injected. They complex with mRNA and target it for RNase degradation.
M2M Unit 1
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