not GL based

Question 1

Tx of subtypes as per KS

Answer 1

atypical : MAOI, SSRI, buproprion

seasonal: light
psychotic: AA, or ECT

Question 2

RF for conversions to BD

Answer 2

Early onset, psychotic features, family history of BAD, mixed features, atypical features

Question 3

old GL? 2006 rec for atypical

Answer 3

Recommendations for Treatment of Major Depressive Disorder with Atypical Features
First-line treatments
• Fluoxetine, moclobemide, sertraline (Level 2 evidence).
Second-line treatments
• Phenelzine (Level 2 evidence).
Third-line treatments
• Imipramine (Level 2 evidence)