NSAIDs

Question 1

Nonselective, irreversible COX 1&@ inhibitors
Reduces platelet production of TXA2

Answer 1

Aspirin

Question 2

Prevent NSAID-induced gastritis

Answer 2

Misoprostol

Question 3

Causes premature closure of PDA

Answer 3

Indomethacin

Question 4

Post-surgical analgesic control, mainly used for analgesia

Answer 4

Ketorolac
Dexketoprofen

Question 5

COX-2 selective NSAIDs

Answer 5

Celecoxib

Question 6

COX-2 inhibitor withdrawn due to increased incidence of thrombosis

Answer 6

Rofecoxib
Valdecoxib

Question 7

Preferential COX-2 selective inhibitor

Answer 7

Meloxicam

Question 8

Selective COX-3 inhibitor

Answer 8

Paracetamol (acetaminophen)
Phenacetin

Question 9

Causes renal papillary necrosis and interstitial nephritis

Answer 9

Phenacetin

Question 10

Preferred antipyretic in children

Answer 10

Paracetamol

Question 11

Antidote for paracetamol overdose

Answer 11

N-acetylcysteine