Nucleic Acids

Question 1

What is the structure of a nucleotide?

Answer 1

• Base
• Pentose sugar
• Phosphate

Question 2

Which nucleotides and purines and which and pyrimidines? Which have two rings?

Answer 2

o	Purine (2 Rings) 
	Adenine
	Guanine
o	Pyrimidine 
	Cytosine
	Thymine
	Uracil

Question 3

What makes up the structure of DNA and RNA?

Answer 3

• 5’ end (phosphate)
• 3’ end (OH)
• Phosphodiester linkages on backbone

Question 4

How many H bonds are between A and T? G and C?

Answer 4

• 2 H bonds between A and T

* 3 H bonds between G and C

Question 5

How is Z form DNA different to A and B form?

Answer 5

It is left handed

Question 6

What is the most common form of DNA?

Answer 6

B form

Question 7

What can allow DNA to bend back on itself?

Answer 7

• DNA can bend back on itself in vitro if it has palindromic sequences

Question 8

What allows RNA to have function?

Answer 8

• RNA can ben back and become functional

* Allows different conformation (e.g. tRNA, ribosome)