5 nutritional supplements:
Creatine name:
alpha-methyl guanidine-acetic acid
Creatine is a natural substance found in the human body in:
- phosphorylated form (phosphorylcreatine, PCr, 30-40%)
Both forms of creatine are ____ and ____ degraded into creatinine.
- irreversibly
Creatine is excreted via the ____ with the _____.
- urine
Rate of creatine:
~2 g/d (~1.6% of total body stores)
Creatine is synthesized endogeneously by:
Ceatine can be consumed in the diet mainly from:
The amount of Cr in the human body varies depending on individual’s ___ ____.
muscle mass
Approximately ___% of the creatine content is found in ____ _____.
- skeletal muscle
A small portion of Cr can also be found in the….
Cr plays an important role in ____ ____ ____ during muscle contractions, specifically involving ____ , ____ ____, _____ ____.
The transfer of ______ group from PCr to ADP regenerates ATP through a reversible reaction catalyzed by the enzyme ____ ____ .
- creatine kinase (CK)
Cr supplementation improves performance (___%) of ____ intensity, ____ duration (< ___) and, in particular, ____ activities that depend on the ___ system.
Cr improves performance for:
Potential ergogenic benefits of Cr supplementation:
In the short term (< 7 days) lean mass gain is related to ____ ____.
water retention (intracellular)
Cr is an ______ active substance.
osmotically
Lean mass gain is expected after ___ weeks of Cr supplementation when combined with ____.
- RE
What happens to body comp if Cr is ingested and no exercise training is performed?
no changes in lean mass, muscle function, or bone health
There are mainly 3 Cr supplementation protocols:
Loading Cr:
- muscle is saturated after 5-7 days
Maintenance Cr:
- muscle is saturated after 4 weeks
Loading + maintenance Cr:
- muscle is saturated after 5-7 days and content is maintained after that