Most likely cause for rapid arterial O2 desaturation during the intubation of a pregnant patient
decreased FRC
FRC = RV + ERV
OB upper airway
Lung physiology
ABG
OxyHgb curve shifts
Ve, Vt, & RR
all increased d/t increased O2 consumption & CO2 production
Lung volumes
O2 consumption
CO
BP
Vascular resistance
CVP & PAOP
no change
cardiac axis deviation
aortocaval compression
IV volume
dilutional anemia
hematologic changes
MAC
30-40% decrease
sensitivity to LA
increase
gastric volume & gastric pH
LES sphincter tone
decreases
Renal
Uterine blood flow
UBF = (Uterine a. pressure - Uterine v. pressure) / uterine vascular resistance
Most important variables that increase drugs across placenta
Drug characteristics that favor placental tranfer