1
Q
what in cigarettes is an appetite surpressant?
A
nicotine
2
Q
what are some ways to target obesity with drugs?
A
- appetite suppression
- decreased absorption
- increased metabolism
3
Q
what is a triacylhlyceride?
A
ester of fatty acids and glycerol
4
Q
can triacylglycerols be absorbed ?
A
no they are too large
5
Q
how are fats absorbed?
A
they are solubilised by formation of micelles with aid detergent such as cholesterol and bile acids
6
Q
what are the two routes for orlistat?
A
- semisynthetic
- synthetic
7
Q
what does semisynthetic mean as a route for orlistat?
A
- production of lipststin by fermentation followed by hydrogenation
- method used by generic manufacturers
8
Q
what does synthetic mean as a route for orlistat?
A
totally synthetic from simple starting materials
-roche process gives higher purity orlistat
Pharmacy Y2- Exam 2
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