What must be present for diagnosis of Pre-term labor?
Contractions + Cervical Dilation from 20-36 weeks GA
Cervical incompetence = cervical dilation w/out contractions
Preterm contractions = contractions w/out cervical dilation
PROM = pt would have hx of “gush of fluid” from vagina (ROM without labor, PPROM is PROM
“Abortion” definition
Pregnancy that ends before 20 weeks gestation or a fetus less than 500 grams.
Chromosomal abnormalities account for 60-80% of these.
Preterm labor – when should you deliver vs. give tocolytics to prevent delivery?
Give tocolytics UNLESS 1 of the following:
Preterm labor – at what fetus age &/or weight do you stop delivery vs. deliver?
Tocolytics if 600-2,500 grams OR 24-33 EGA.
Deliver if >2,500 grams or 34-37 EGA.
Preterm labor – if you need to stop delivery, what do you give?
Betamethasone to mature lungs (12g IM x 2 doses 24hrs apart)
+
Tocolytics: Magnesium sulfate, CCBs, or Terbutaline
**Betamethasone effects take 24 hours to work, peak at 48 hours, & last for 7 days.
What do you need to check when giving Magnesium Sulfate & why?
Check Deep Tendon Reflexes,
Workup of suspected PROM?
Sterile speculum examination to confirm the fluid as amniotic fluid:
PROM management
If + Chorioamnionitis:
– delivery now
If at term, w/out chorioamnionitis:
– wait 6-12 hrs for SVB, then induce labor if doesn’t occur
If preterm, w/out chorioamnionitis:
– Give Betamethasone + Tocolytics + ABX (ampicillin & azithromycin)
**do fewer exams to prevent chorioamnionitis
Placenta previa presentation?
Vaginal bleeding in 3rd trimester – next step?
Trans-abdominal ultrasound to see if placenta is lying in the uterus.
**DVE & transvaginal exam NOT done b/c they can separate the placenta from the uterus if placenta previa is present, causing further bleeding.
Placental abruption – what is it & what are some risk factors?
Premature separation of placenta from uterus, causing tearing of blood vessels & hemorrhaging into separated space.
Risk Factors:
Polyhydramnios – causes?
Oligohydramnios – causes?
Prune belly: lack of abdominal muscles, so unable to bear down & pee
– Treatment = serial Foley cath placements
When is Prenatal antibody screening (for Rh-antibody) done for Rh-negative mothers?
Screened at initial visit, then it is done again @ 28 & 35 weeks
Management of Rh-negative mom with Rh-positive fetus?
Indirect antiglobulin test.
If positive for Rh-antibodies, then:
– Amniocentesis @ 16-20 weeks to evaluate fetal cells for Bilirubin levels
If low or medium, repeat amniocentesis in 2-3 wks or 1-2 wks, respectively.
If high bilirubin, to percutaneous umbilical blood sample to check fetal hematocrit & give intrauterine transfusion if low.
Treatment for pregnant patient w/ chronic HTN @ baseline?
Methyldopa, Labetalol, or Nifedipine
Gestational HTN definition?
BP over 140/90 that starts after 20 wks gestation.
There is no proteinuria & no edema.
**Treat only during pregnancy w/ Methyldopa, Labetalol, or Nifedipine
Preeclampsia – Tx?
If mild & at term: Induce delivery
If mild & preterm: give Betamethasone & Magnesium Sulfate as seizure proph & tocolytic
If severe (>160/110): give Mag sulfate (seizure proph) & Hydralazine (control BP), then follow above rules
Eclampsia – Tx?
Seizure control – Magnesium Sulfate
BP control – Hydralazine
Deliver the baby immediately after doing these 2 things.
**Same treatment for HELLP syndrome.
Blood sugar goals for gestational diabetes?
Fasting BS < 95 mg/dL
Postprandial BS < 140 mg/dL
Macrosomia definition
Fetuses w/ estimated birth weight over 4500 grams
** on PE, the fundal height will be at least 3cm greater than the gestational age. In normal-sized babies, fundal height should equal gestational age in weeks.
Macrosomia – Tx?
Induction of labor if lungs are mature before fetus is >4500 grams
C-section if fetus is >4500 grams
Biophysical Profile (BPP) – components?
Cause of early decels?
Head compression